Table 1.

Mean amounts of food eaten (in grams) and latency to start eating (in seconds) as well as total and reinforced wheel turns observed during the 3 d training period previous to the pharmacological experiments conducted on the ChR2 mice for the feeding and optical self-stimulation studies

TrainingAmount eaten (g)Latency to eat (s)Total wheel turnsReinforced wheel turns
No lightLightActiveInactive
Day 10.24 ± 0.0657.94 ± 1.5432.89 ± 7.79693.48 ± 125.9532.57 ± 5.45112.81 ± 9.70
Day 20.31 ± 0.0660 ± 025.11 ± 5.751148.88 ± 106.3054.19 ± 22.99143.38 ± 11.13
Day 30.32 ± 0.0660 ± 026.77 ± 6.951086.86 ± 142.1340.52 ± 9.87143.52 ± 15.11
  • The statistical analyses for each variable are as follows: amount eaten, main effect of days, F(2,12) = 2.61, p = 0.11, n.s.; latency to eat, χ2 = 30.56, p < 0.001, no significant difference between the latencies to eat observed during the no light trials during the 3 training days, as well as no differences between the latencies to eat observed during the light trials during the 3 training days; total wheel turns, main effect of days, F(2,12) = 4.88, p < 0.05; main effect of wheel, F(1,6) = 174.15, p < 0.001; days by wheel interaction, F(2,12) = 3.74, p = 0.06, n.s.; reinforced wheel turns, main effect of days, F(2,12) = 3.22, p = 0.08, n.s.