Exploration time for infusion animals performing the OIP
| Drug | Dose (μg/μl) | Sample phase (s) | Test phase (s) |
|---|---|---|---|
| CX546 | 0.0 | 103.4 ± 4.9 | 35.1 ± 3.8 |
| 0.1 | 113.6 ± 7.5 | 43.7 ± 5.9 | |
| 0.3 | 112.2 ± 7.6 | 40.5 ± 4.6 | |
| CX516 | 0.0 | 114.4 ± 9.0 | 47.8 ± 3.2 |
| 0.1 | 98.7 ± 4.1 | 51.2 ± 5.7 | |
| 0.3 | 120.6 ± 6.9 | 48.9 ± 8.8 | |
| MMPIP | 0.0 | 105.3 ± 6.4 | 38.4 ± 3.0 |
| 1.0 | 116.4 ± 11.5 | 48.7 ± 5.6 |
The total amount of exploration performed during the sample phase (5 min) and test phase (3 min) of the OIP was unaffected by drug treatment. Data are shown as mean ± SEM (CX546, n = 9; CX516, n = 8; MMPIP, n = 10).