Intrinsic properties of post-SNI and pre-SNI MGE cells
| Post-SNI | Uninjured | Mann–Whitney test (p) | |
|---|---|---|---|
| No. of mice | 7 | 16 | |
| Membrane potential (mV) | −55.52 ± 1.89 (n = 21) | −63.56 ± 1.7 (n = 32) | 0.003 |
| Input resistance (MΩ) | 336.55 ± 55.05 (n = 21) | 399.36 ± 43.53 (n = 32) | 0.391 |
| Capacitance (pF) | 156.73 ± 33.15 (n = 21) | 126.16 ± 13 (n = 32) | 0.274 |
| Firing frequency (Hz) | 23.4 ± 4.61 (n = 8) | 32.4 ± 3.17 (n = 10) | 0.191 |
| AP threshold (mV) | −38.64 ± 7.64 (n = 13) | −43.5 ± 3.5 (n = 29) | 0.053 |
| AP amplitude (mV) | 43.73 ± 4.47 (n = 13) | 60.6 ± 3.1 (n = 29) | 0.013 |
| AP half-width (ms) | 2.55 ± 0.41 (n = 13) | 1.7 ± 0.2 (n = 29) | 0.002 |
| AP AHP amplitude (mV) | 6.05 ± 1.93 (n = 11) | 2.6 ± 2.2 (n = 29) | 0.274 |
| Firing pattern | |||
| Tonic | 42.1% | 67.7% | χ2 = 13.47 |
| Single | 36.8% | 6.5% | |
| Initial bursting | 0 | 12.9% | |
| Irregular | 21.1% | 3.2% | p = 0.009 |
| Delayed | 0 | 9.7% |