Overview of the mechanisms involved in the suppression of excitatory and inhibitory currents in HD RGCs and the degree to which these currents are suppressed
| Response | Excitation suppression | Inhibition suppression | Mechanism of surround suppression |
|---|---|---|---|
| HD1 | |||
| ON | 85 ± 10% | 5 ± 1% | |
| OFF | 75 ± 8% | 8 ± 3% | Presynaptic and postsynaptic inhibition |
| HD2 | |||
| ON | 53 ± 7% | 60 ± 6% | |
| OFF | 78 ± 4% | No inhibition | Presynaptic inhibition |
| UHD | |||
| ON | 90 ± 7% | 23 ± 7% | |
| OFF | 85 ± 4% | 13 ± 3% | Strong presynaptic and postsynaptic inhibition |