Table 3.

Active membrane properties in response to the first suprathreshold current pulse in WT and Fmr1 KO LSO neuronsa

AP width (ms)Latency (ms)AP amplitude (pA)Voltage threshold (mV)
P8
    WT (n = 17)0.57 ± 0.0410.09 ± 0.9176.06 ± 1.6−28.27 ± 1.1
    Fmr1 KO (n = 16)0.60 ± 0.0417.24 ± 1.3680.26 ± 1.9−30.91 ± 1.0
    p>0.99<0.0010.670.59
P14
    WT (n = 16)0.376 ± 0.0344.73 ± 0.5667.04 ± 1.57−26.49 ± 1.0
    Fmr1 KO (n = 15)0.26 ± 0.012.25 ± 0.1866.50 ± 1.47−29.43 ± 0.9
    p>0.990.04>0.990.69
P21
    WT (n = 39)0.21 ± 0.0053.11 ± 0.1865.49 ± 1.1−26.24 ± 0.6
    Fmr1 KO (n = 20)0.24 ± 0.012.28 ± 0.166.74 ± 0.91−24.59 ± 1.3
    p>0.990.72>0.99>0.99
  • ap values: two-way ANOVA followed by Bonferroni post-tests.