INaP | IA | IK | ILVA | IHVA | IS | Ih | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
m | h | m | h1 | h2 | m | m | h | m | h1 | h2 | m | h1 | h2 | |
Vh (mV) | −41.5 | −47.4 | −29.4b | −60b | −60b | −19.7b | −51.4b | −80.1b | −11b | −36.6b | −36.6b | −45 | −77.4 | −77.4 |
k (mV) | −3.0 | 8.2 | −6.64b | 4.26b | 4.26b | −12.3b | −4.07b | 5.5b | −7b | 14.6b | 14.6b | −12 | 9.2 | 9.2 |
τ (ms) | 0.4 | Eq. 14 | Eq. 14 | 7.67b | 100b | Eq. 14 | Eq. 14 | 250b | 0.816b | 53.4b | 728b | 1500 | Eq. 15 | Eq. 15 |
a | — | 67.3 | −2.91b | — | — | 23.8b | 31.3b | — | — | — | — | — | −89.8 | −82.6 |
b | — | −27.5 | 25.6b | — | — | 18b | 10.1b | — | — | — | — | — | 11.6 | 25.7 |
c | — | 67.3 | 65.3b | — | — | 23.8b | 31.3b | — | — | — | — | — | 35.8 | 370.9 |
d | — | 27.5 | −10.6b | — | — | −18b | −10.1b | — | — | — | — | — | 7.6 | 54.1 |
e | — | 574.5 | 1 | — | — | 10.6b | 109b | — | — | — | — | — | — | — |
f | — | 62.6 | 0.0527b | — | — | 0 | 0.0391b | — | — | — | — | — | — | — |
↵aVh and k are the voltage at half-activation or inactivation and the steepness of the steady-state function. τ is the time constant that is voltage-independent for mNap, h1A, h2A, hLVA, mHVA, h1HVA, h2HVA, and ms. For hNaP, mA, mK, mLVA, h1h, and h2h, τ is voltage-dependent and governed by Equation 14 (a, b, c, and d are in mV, e and f are in ms) or Equation 15 (a and b are in mV, and c is in ms).
↵bParameters that were reestimated from Moran et al. (2016).