Table 6.

BOLD responses to the nonpainful and painful phase of ascending thermal stimulation in the brain during the baseline sessiona

Regionxyztp
Nonpainful phase
    Anterior cingulate cortex824303.31<0.001
    Calcarine gyrus−12−10006.95<0.001
    Cerebellum28−72−224.43<0.001
42−54−323.68<0.001
−36−66−523.39<0.001
    Inferior frontal gyrus3828−25.12<0.001
−546103.51<0.001
    Inferior parietal lobule−36−48405.57<0.001
−50−50524.68<0.001
    Left insula−322684.90<0.001
    Middle frontal gyrus3852204.80<0.001
−3648204.44<0.001
    Middle orbital gyrus404843.37<0.001
    Postcentral gyrus−62−22244.20<0.001
    Posterior cingulate cortex−4−26284.83<0.001
6−14303.17<0.001
    Posterior-medial frontal412524.24<0.001
    Precuneus−14−64363.77<0.001
12−66363.37<0.001
    Rolandic operculum56−24244.54<0.001
46−24283.17<0.001
    Superior orbital gyrus1816−163.62<0.001
    Supramarginal gyrus52−42346.17<0.001
Painful phase
    Calcarine gyrus−8−98−65.06<0.001
    Cerebellum−32−56−347.82<0.001
−30−66−307.79<0.001
−10−74−307.41<0.001
34−56−325.13<0.001
26−46−303.47<0.001
38−66−283.31<0.001
18−70−523.66<0.001
20−64−583.54<0.001
14−76−483.52<0.001
2−56−323.65<0.001
14−58−323.19<0.001
38−56−523.26<0.001
−10−58−543.19<0.001
20−50−243.17<0.001
    Inferior parietal lobule−36−48405.66<0.001
−54−50505.39<0.001
−56−38525.08<0.001
    Inferior temporal gyrus60−30−184.92<0.001
    Insula−3418−28.97<0.001
    Linual gyrus−10−8604.98<0.001
14−9024.21<0.001
    Middle frontal gyrus−5210444.21<0.001
    Middle temporal gyrus62−32−85.33<0.001
62−4664.11<0.001
    Precentral gyrus−42−2424.80<0.001
−44−2584.03<0.001
    Precuneus14−62384.16<0.001
−12−64363.61<0.001
    Superior medial gyrus020449.14<0.001
48−4883.36<0.001
    Supramarginal gyrus52−36468.69<0.001
  • aCoordinates are denoted by x, y, z in mm (MNI space), and strength of activation is expressed in t scores (df = 120).