Table 3.

Neural correlates of the expected cost of mental effort for the chosen option revealed by using GLM2

AreaLeft, right, bilateralClusterPeak (T)MNI coordinates (mm)
Sizep(FWE)xyz
A, Experiment 1
     Positive correlation
        MFG/inferior frontal gyrus/anterior insulaRight514<0.0015.630504
        aMFGLeft1030.0335.5−30477
        dmFC/dACCBilateral1960.0025.701449
        Inferior parietal lobuleRight1440.0095.045−5249
     Negative correlation
        Rostromedial PFCBilateral2330.0016.0−95316
        vmPFC/striatumBilateral392<0.0017.5341−17
        Primary motor cortex/primary somatosensory cortexRight1250.0175.442−2264
        Temporal lobeRight1900.0035.369−3413
        Parietal operculum/temporal lobeLeft1217<0.0016.8−42−3725
        PrecuneusBilateral2180.0015.4−3−5816
B, Experiment 2
     Positive correlation
        Anterior insula/aMFG/orbitofrontal cortexLeft266<0.0017.6−27234
        dmFC/dACC/superior frontal gyrusBilateral489<0.0017.362049
        Anterior insula/aMFG/orbitofrontal cortexRight663<0.00112.933204
        Inferior parietal lobule/precuneusRight262<0.0015.445−4955
        CerebellumLeft1410.0078.0−18−61−41
     Negative correlation
        vmPFCaLeft120.8184.5−335−20
        StriatumaBilateral480.2014.905−8
C, Conjunction analysis
     Positive correlation (strict maskb)
        aMFGRight2230.0026.033474
        dmFC/dACCBilateral1360.0185.832046
        Inferior parietal lobulecRight910.0644.945−4949
     Negative correlation (relaxed maskd)
        vmPFCBilateral1310.0204.8−635−17
  • Configurations are the same as those in Table 2, except that GLM2 was used and C corresponds to Figure 9B.

  • aVoxel-level uncorrected p < 0.001 and voxel size ≥5.

  • bA binary mask consisting of common voxels at cluster-level FWE corrected p < 0.05 and voxel-level uncorrected p < 0.001.

  • cCluster-level uncorrected p < 0.05 and voxel-level uncorrected p < 0.001; with a binary mask consisting of common voxels at cluster-level FWE corrected p < 0.05 and voxel-level uncorrected p < 0.001.

  • dA binary mask consisting of common voxels at voxel-level uncorrected p < 0.01.