Table 3.

Intrinsic membrane properties of SPNs

	dSPNs			iSPNs
	WT Saline (7)	BAC-Pitx3^−/−		WT Saline (9)	BAC-Pitx3^−/−
	WT Saline (7)	Saline (8)	l-DOPA (9)	WT Saline (9)	Saline (7)	l-DOPA (11)
Passive membrane properties
RMP (mV)	−88.9 ± 4.0	−89.6 ± 3.0	−91.7 ± 3.4	−89.4 ± 1.9	−90.2 ± 4.5	−92.9 ± 1.4
R_in (MΩ)	46.31 ± 5.2	44.7 ± 5.70	33.2 ± 1.5	41.3 ± 3.2	39.9 ± 5.4	37.7 ± 3.3
Active membrane properties
AP threshold (mV)	−45.5 ± 1.6	−51.7 ± 1.7^*	−48.6 ± 2.2	−45.9 ± 2.2	−53.7 ± 1.1^*	−48.4 ± 1.1
AP amplitude (mV)	86.9 ± 6.9	87.3 ± 8.1	76.3 ± 11.6	87.4 ± 5.1	78.7 ± 6.4	83.8 ± 5.3
AP width (ms)	0.71 ± 0.05	0.74 ± 0.11	0.54 ± 0.11	0.72 ± 0.06	0.77 ± 0.12	0.57 ± 0.04
Rheobase (nA)	0.31 ± 0.02	0.22 ± 0.02^*	0.21 ± 0.01^**	0.20 ± 0.04	0.21 ± 0.03	0.29 ± 0.02
AHP amplitude (mV)	4.96 ± 0.98	5.50 ± 0.94	5.35 ± 2.38	4.96 ± 0.98	5.83 ± 1.12	7.27 ± 1.33

Data are presented as the mean ± SEM. The number of SPNs recorded in each condition is expressed in parentheses following the condition.
↵*p < 0.05;
↵**p < 0.01 vs WT mice; one-way ANOVA following Bonferroni's post-test.