Nerve conduction and repetitive stimulation studies on 68-week-old wild-type and Col13a1−/− female micea
| Nerve | Type | Parameter | Col13a1+/+ (N = 5) (mean ± SEM) | Col13a1−/− (N = 5) (mean ± SEM) | p |
|---|---|---|---|---|---|
| Tail | Sensory | SCV (m/s) | 40.8 ± 0.9 | 35.6 ± 1.9 | 0.095 |
| SNAP (μV) | 410.8 ± 54.5 | 429.6 ± 39.0 | 0.786 | ||
| Motor | Latency (ms) | 0.8 ± 0.0 | 0.9 ± 0.0 | 0.056 | |
| Amplitude (mV) | 0.3 ± 0.0 | 0.2 ± 0.0 | 0.444 | ||
| Tibial | Motor | MCV (m/s) | 36.6 ± 1.4 | 34.9 ± 3.3 | 0.660 |
| Latency (ms) | 1.4 ± 0.0 | 1.6 ± 0.1 | 0.117 | ||
| CMAP 1 (mV) | 6.2 ± 1.8 | 3.4 ± 0.9 | 0.195 | ||
| CMAP 2 (mV) | 7.1 ± 1.6 | 5.4 ± 1.9 | 0.522 | ||
| F-latency (ms) | 5.7 ± 0.1 | 6.1 ± 0.1 | 0.056 | ||
| Ischial | Motor response | Latency (ms) | 1.7 ± 0.1 | 1.8 ± 0.0 | 0.206 |
| Amplitude (mV) | 59.3 ± 7.1 | 56.3 ± 9.8 | 0.808 | ||
| Ischial | Repetitive (3 Hz) | CMAP change (5th/2nd; %) | +3.0 ± 0.4 | +3.4 ± 1.1 | 0.572 |
↵aSCV, Sensory conduction velocity; MCV, motor conduction velocity; SNAP, sensory nerve action potential; CMAP 1, mean compound action potential with stimulation at the sciatic notch; CMAP 2, mean compound action potential with stimulation at the ankle.