Table 2.

Parameter values for the activation and inactivation variables appearing in Equations 1315a

INaPIAIKILVAIHVAISIh
mhmh1h2mmhmh1h2mh1h2
Vh (mV)−41.5−47.4−29.4bb−19.7−51.4−80.1−11−36.6−36.6−45−77.4−77.4
k (mV)−3.08.2−6.644.264.26−12.3−4.075.5−714.614.6−129.29.2
τ (ms)0.4Eq. 14Eq. 147.67100Eq. 14Eq. 142500.81653.47281500Eq. 15Eq. 15
a67.3−2.9123.831.3−89.8−82.6
b−27.525.61810.111.625.7
c67.365.323.831.335.8370.9
d27.5−10.6−18−10.17.654.1
e574.5110.6109
f62.60.052700.0391
  • aVh and k are the voltage at half-activation or inactivation and the steepness of the steady-state function. τ, Time constant that is voltage independent for mNap, h1A, h2A, hLVA, mHVA, h1HVA, h2HVA, and ms. For hNaP, mA, mK, mLVA, h1h, and h2h, τ is voltage-dependent and governed by Equation 14 (a, b, c, and d are in mV, e and f are in ms) or Equation 15 (a and b are in mV, and c is in ms).

  • bSee Table 4.