Regular ArticleLong-Term Survival of Human Central Nervous System Progenitor Cells Transplanted into a Rat Model of Parkinson's Disease☆
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Stem-Cell Research of Parkinson Disease: Bibliometric Analysis of Research Productivity from 1999 to 2018
2020, World NeurosurgeryCitation Excerpt :The number of publications about neural stem cells in PD research increased steadily (30 during 1999–2003; 72 during 2004–2008; 101 during 2009–2013; and 112 during 2014–2018). Experimental studies in rodent and primate models of PD have confirmed the survival, differentiation, migration, and function of NSCs.32-34 The unpublished data from a single-arm clinical trial (clinical trial ID: NCT03128450; https://clinicaltrials.gov) have assessed the safety and efficacy of human NSCs transplantation in PD patients from Suzhou, China, allowing for an upcoming randomized controlled study.
A novel treatment for Parkinson's disease and ALS: Combined cell and gene therapies
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2017, Progress in NeurobiologyCell-based therapeutic strategies for replacement and preservation in retinal degenerative diseases
2017, Progress in Retinal and Eye ResearchCitation Excerpt :Another stem/progenitor cell type that is often utilized in preservation strategies is neural stem/progenitor cells (NSCs/NPCs). Similar to RSCs/RPCs, NSCs/NPCs can be derived from fetal brain tissue, ESCs, or iPSCs (Sareen et al., 2014; Shelley et al., 2014; Svendsen et al., 1997). NSCs/NPCs are self-renewing, multipotent cells that are able to differentiate into cells of the nervous system.
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W. M. CowanE. M. ShooterC. F. StevensR. F. Thompson, Eds.
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