Regular ArticleSelective Synaptic Plasticity within the Cerebellar Cortex Following Complex Motor Skill Learning
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2023, Psychology of Sport and ExerciseNeuroplasticity induced by the retention period of a complex motor skill learning in rats
2021, Behavioural Brain ResearchCitation Excerpt :In addition, CB appears to be predominantly engaged at the beginning of new complex motor practice. AE data corroborate previous studies which demonstrated that long AE training (10 and 38 days) induced an increase in the number of synapses per Purkinje cell, and improved motor performance during training of a new motor skill [14,80]. These data suggest that enhanced motor performance after a long period of training may be associated with cerebellar cortex structural and functional adaptation.
Motor learning rapidly increases synaptogenesis and astrocytic structural plasticity in the rat cerebellum
2021, Neurobiology of Learning and MemoryCitation Excerpt :The primary conclusion of this experiment was that learning new complex movements required the addition of synapses, but engaging in repetitive, well-established movements, such as running, only increased activity of existing synapses (Black et al., 1990). This synaptogenesis was later attributed to the addition of parallel fiber-Purkinje cell synapses (Kleim et al., 1998). An increase in both single synapses between one parallel fiber varicosity and one Purkinje cell spine as well as multi-synapses between one parallel fiber varicosity and two Purkinje cell spines, have been identified in male rats that trained on the acrobatic course for 20 days (Federmeier et al., 2002; Kim et al., 2002).
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We thank Lori Rolando and Ted Glaser for their assistance with training the animals, the Beckman Institute Optical Visualization Facility for use of their stereology system, and the University of Illinois Center for Electron Microscopy for the use of their facilities. Work was supported by AG10154, MH35321, AA09838, the Kiwanis foundation, the Retirement Research Foundation, and an NSERC fellowship. Address correspondence to William T. Greenough, Beckman Institute, 405 N. Mathews Ave., Urbana, IL 61801 USA. Fax: (217) 244-5180. E-mail:[email protected].