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Enteric Neurobiology: Discoveries and Directions

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Book cover The Enteric Nervous System

Part of the book series: Advances in Experimental Medicine and Biology ((ANS,volume 891))

Abstract

Discovery and documentation of noncholinergic-nonadrenergic neurotransmission in the enteric nervous system started a revolution in mechanisms of neural control of the digestive tract that continues into a twenty-first century era of translational gastroenterology, which is now firmly embedded in the term, neurogastroenterology. This chapter, on Enteric Neurobiology: Discoveries and Directions, tracks the step-by-step advances in enteric neuronal electrophysiology and synaptic behavior and progresses to the higher order functions of central pattern generators, hard wired synaptic circuits and libraries of neural programs in the brain-in-the-gut that underlie the several different patterns of motility and secretory behaviors that occur in the specialized, serially-connected compartments extending from the esophagus to the anus.

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Authors and Affiliations

  1. Department of Physiology and Cell Biology, The Ohio State University College of Medicine, 304 Hamilton Hall, 1645 Neil Avenue, Columbus, OH, 43210-1218, USA

    Jackie D. Wood

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  1. Jackie D. Wood
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Correspondence to Jackie D. Wood .

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Editors and Affiliations

  1. Discipline of Medicine, University of Adelaide, Adelaide, South Australia, Australia

    Stuart Brierley

  2. Department of Human Physiology, School of Medicine, Flinders University,, Adelaide, South Australia, Australia

    Marcello Costa

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Wood, J.D. (2016). Enteric Neurobiology: Discoveries and Directions. In: Brierley, S., Costa, M. (eds) The Enteric Nervous System. Advances in Experimental Medicine and Biology(), vol 891. Springer, Cham. https://doi.org/10.1007/978-3-319-27592-5_17

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