Abstract
The cortical auditory fields of the two hemispheres are interconnected via the corpus callosum. We have investigated the topographical arrangement of auditory callosal axons in the cat. Following circumscribed biocytin injections in the primary (AI), secondary (AII), anterior (AAF) and posterior (PAF) auditory fields, labelled axons have been found in the posterior two-thirds of the corpus callosum. Callosal axons labelled by small individual cortical injections did not form a tight bundle at the callosal midsagittal plane but spread over as much as one-third of the corpus callosum. Axons originating from different auditory fields were roughly topographically ordered, reflecting to some extent the rostro-caudal position of the field of origin. Axons from AAF crossed on average more rostrally than axons from AI; the latter crossed more rostrally than axons from PAF and AIL Callosal axons originating in a discrete part of the cortex travelled first in a relatively tight bundle to the telo-diencephalic junction and then dispersed progressively. In conclusion, the cat corpus callosum does not contain a sector reserved for auditory axons, nor a strictly topographically ordered auditory pathway. This observation is of relevance to neuropsychological and neuropathological observations in man.
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Bajo VM, Rouiller EM, Welker E, Clarke S, Villa AEP, Ribaupierre Y de, Ribaupierre F de (1995) Morphology and spatial distribution of corticothalamic terminals originating from the cat auditory cortex. Hear Res 83: 161–174
Berlucchi G, Gazzaniga MS, Rizzolatti G (1967) Microelectrode analysis of transfer of visual information by the corpus callosum. Arch Ital Biol 105: 583–596
Clarke S, Kraftsik R, Van der Loos H, Innocenti GM (1989) Forms and measures of adult and developing human corpus callosum: is there sexual dimorphism? J Comp Neurol 280: 231–253
Clarke S, Ribaupierre F de, Rouiller EM, Ribaupierre Y de (1993) Several neuronal and axonal types form long intrinsic connections in the cat primary auditory cortical field (AI). Anat Embryol 188: 117–138
Clarke S, Bajo-Lorenzana V, Rouiller EM, Ribaupierre F de, Kraftsik R (1994) Auditory axons in the cat corpus callosum (abstract). Experientia 50: 69
Hubel DH, Wiesel TN (1967) Cortical and callosal connections concerned with the vertical meridian of visual fields in the cat. J Neurophysiol 30: 1561–1573
Imig TJ, Adrian HO (1977) Binaural columns in the primary field (AI) of cat auditory cortex. Brain Res 138: 241–257
Imig TJ, Brugge JF (1978) Sources and terminations of callosal axons related to binaural and frequency maps in primary auditory cortex of the cat. J Comp Neurol 182: 637–660
Imig TJ, Reale RA (1980) Patterns of cortico-cortical connections related to tonotopic maps in cat auditory cortex. J Comp Neurol 192: 293–332
Innocenti GM (1980) The primary visual pathway through the corpus callosum: morphological and functional aspects in the cat. Arch Ital Biol 118: 124–188
Innocenti GM (1986) General organization of callosal connections in the cerebral cortex. In: Jones EG, Peters A (eds) Cerebral Cortex, vol 5. Plenum, New York, pp 291–353
Innocenti GM, Clarke S (1984) Bilateral transitory projections to visual areas from auditory cortex in kittens. Brain Res Dev Brain Res 14: 143–148
King MA, Louis PM, Hunter BE, Walker DW (1989) Biocytin: a versatile anterograde neuroanatomical tract-tracing alternative. Brain Res 497: 361–367
Knight PL (1977) Representation of the cochlea within the anterior auditory field (AAF) of the cat. Brain Res 130: 447–467
Koppel H, Innocenti GM (1983) Is there a genuine exuberancy of callosal projections in development? A quantitative electron microscopic study in the cat. Neurosci Lett 41: 33–40
Merzenich MM, Knight PL, Roth GL (1975) Representation of cochlea within primary auditory cortex in the cat. J Neurophysiol 38: 231–249
Middlebrooks JC, Dikes RW, Merzenich MM (1980) Binaural response — specific bands in primary auditory cortex (AI) of the cat: topographical organization orthogonal to isofrequency contours. Brain Res 181: 31–48
Nakamura H, Kanaseki T (1989) Topography of the corpus callosum in the cat. Brain Res 485: 171–175
Payne BR, Siwek DF (1991) The visual map in the corpus callosum of the cat. Cereb Cortex 1: 173–188
Reale RA, Imig TJ (1980) Tonotopic organization of auditory cortex in the cat. J Comp Neurol 192: 265–291
Rouiller EM, Simm GM, Villa AEP, Ribaupierre Y de, Ribaupierre F de (1991) Auditory corticocortical interconnections in the cat: evidence for parallel and hierarchical arrangement of the auditory cortical areas. Exp Brain Res 86: 483–505
Trevarthen C (1990) Integrative functions of the cerebral commissures. In: Boiler F, Grafman J (eds) Handbook of Neuropsychology, vol 4. Eisevier, Amsterdam, pp 49–83
Van Buren JM, Borke RC (1972) Variations and connections of the human thalamus. 1. The nuclei and cerebral connections of the human thalamus. Springer, Berlin Heidelberg New York
Winer JA (1992) The functional architecture of the medial geniculate body and the primary auditory cortex. In: Webster DB, Popper AN, Fay RR (eds) The mammalian auditory pathway: neuroanatomy. Springer, Berlin Heidelberg New York, pp 222–409
Zingerle H (1912) Ueber einseitigen Schläfenlappendefekt beim Menschen. J Psychol Neurol 18: 205–238
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Clarke, S., de Ribaupierre, F., Bajo, V.M. et al. The auditory pathway in cat corpus callosum. Exp Brain Res 104, 534–540 (1995). https://doi.org/10.1007/BF00231988
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DOI: https://doi.org/10.1007/BF00231988