Zusammenfassung
Die Blut-Perilymph-Schranke wurde mit der Gefrierbruch-Technik elektronenmikroskopisch untersucht. Sie ist durch die vesikelarmen kontinuierlichen Kapillar-Endothelzellen und deren “tight junctions” vom mesothelialen Typ charakterisiert. Im Gegensatz dazu weisen die Endothelzellen der Stria vascularis-Gefäße eine außerordentliche mikropinocytotische Aktivität und eine hohe Partikeldichte der Zellmembranen auf. Auch im Plexus cochlearis liegen besondere Verhältnisse vor. Generell ist die Blut-Perilymph-Schranke morphologisch der Blut-Hirn-Schranke ähnlich.
Summary
Freeze fracture replicas of the guinea pig inner ear were studied under the electron microscope to define the blood-perilymph barrier morphologically. This barrier is represented basically by the continuous endothelium of the inner ear capillaries. The endothelial cells contain only a few micropinocytotic vesicles in contrast to those of the stria vascularis vessels. The cochlear plexus also exhibits some special differences. Tight junctions of the continuous mesothelial type connect the endothelial cells of the inner ear capillaries. Cell membranes of these cells possess a lower particle density than those of the stria vascularis vessels. In general, the blood-perilymph barrier is morphologically similar to the blood-brain barrier.
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Supported by grants of the “Deutsche Forschungsgemeinschaft”
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Jahnke, K. The blood-perilymph barrier. Arch Otorhinolaryngol 228, 29–34 (1980). https://doi.org/10.1007/BF00455891
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DOI: https://doi.org/10.1007/BF00455891
Schlüsselwörter
- Innenohrkapillaren
- Gefrierbruch-Technik
- Kontinuierliche
- Kapillar-Endothelzellen
- „tight junctions“
- Schranken
- Porensysteme