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Changes in body temperature produced by injecting prostaglandin E1, EGTA and bacterial endotoxins into the PO/AH region and the medulla oblongata of the rat

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Résumé

La prostaglandine E1 a causé de l'hyperthermie si on l'injectait dans la région préoptique/hypothalamique antérieure/des rats et de l'hypothermie au niveau de la région médullaire oblongue. L'EGTA, le Piromen et le vaccin typhoïdes ont rarement causé des changements parallèles dans la température rectale si on les injectait dans les deux régions cérébrales.

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Authors and Affiliations

  1. Departments of Psychiatry, Physiology and Pharmacology, Southwestern Medical School, The University of Texas Health Science Center at Dallas, 75235, Dallas, Texas, USA

    J. M. Lipton, J. P. Welch & W. G. Clark

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  1. J. M. Lipton
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  2. J. P. Welch
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  3. W. G. Clark
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Additional information

This research was supported by PHS Research Grant No. 1-R01-NS-10046-01 from the National Institute of Neurological Diseases and Stroke. We thank Dr.J. Pike of Upjohn Laboratories for supplying the PGE1.

Medical student fellow in Psychiatry. Supported by the Hogg Foundation and PHS Grant No. 5 TO2 MH 5928 from the National Institute of Mental Health.

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Lipton, J.M., Welch, J.P. & Clark, W.G. Changes in body temperature produced by injecting prostaglandin E1, EGTA and bacterial endotoxins into the PO/AH region and the medulla oblongata of the rat. Experientia 29, 806–808 (1973). https://doi.org/10.1007/BF01946298

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