DOPA decar☐ylase in the developing rat brain
References (16)
- et al.
Preparation and properties of a homogeneous aromaticl-amino acid decar☐ylase from hog kidney
Arch. Biochem. Biophys.
(1970) - et al.
Aromaticl-amino acid decar☐ylase
J. biol. Chem.
(1962) - et al.
Schedule of appearance of 5-hydroxytryptamine (serotonin) and associated enzymes in the developing rat brain
J. Neurochem.
(1965) - et al.
Development of the uptake and storage ofl-[3H]-norepinephrine in the rat brain
J. Neurochem.
(1971) - et al.
Dopamine-β-hydroxylase in the rat brain: developmental characteristics
J. Neurochem.
(1972) - et al.
Tyrosine hydroxylase in rat brain: developmental characteristics
J. Neurochem.
(1972) - et al.
Regional studies of catecholamines in rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]DOPA in various regions of the brain
J. Neurochem.
(1966) Role ofl-dopa decar☐ylase in the biosynthesis of catecholamines in nervous tissue and the adrenal medulla
Pharmacol. Rev.
(1959)
Cited by (92)
Norepinephrine, neurodevelopment and behavior
2020, Neurochemistry InternationalCitation Excerpt :Robust synaptogenesis of noradrenergic pathways appears to be between PNDs10-15 and 20–30 (Murrin et al., 2007) and the density of noradrenergic innervation reaches adult value in the third to fourth postnatal weeks (Coyle, 1977; Berger and Verney, 1984; Murrin et al., 2007). The enzymes involved in catecholamine synthesis are present in the rat brain at GD15 (Coyle and Axelrod, 1972a,b; Lamprecht and Coyle, 1972). At this time, the level of NE is 2% of the adult level (Coyle and Henry, 1973), and reaches its adult level within 5–10 weeks of age (Kohno et al., 1982), thus, although LC noradrenergic neurons appear early in fetal brain development, the majority of noradrenergic maturity is acquired during 5–10 weeks of age.
Comparison of the maturation of the adrenergic and serotonergic neurotransmitter systems in the brain: Implications for differential drug effects on juveniles and adults
2007, Biochemical PharmacologyCitation Excerpt :The two enzymes following the rate-limiting TH in norepinephrine synthesis are AADC and DBH. The developmental pattern of both follows closely the patterns for TH and norepinephrine [42,43]. Studies on the development of the serotonin synthetic system are limited.
Molecular characterization of a metastatic neuroendocrine cell cancer arising in the prostates of transgenic mice
2002, Journal of Biological ChemistryCitation Excerpt :Sections were surveyed, in a single-blinded fashion, for cells containing immunoreactive protein. Tissues were Dounce-homogenized in ice-cold homogenization buffer (50 mm Tris, pH 6.0, 0.2% Triton X-100, 1× complete protease inhibitor (Roche Molecular Biochemicals)) (15). The homogenate was centrifuged at 10,000 × g for 10 min at 4 °C.
Age-related changes in the blood-brain barrier
1997, Experimental GerontologyEarly induction of rat brain tryptophan hydroxylase (TPH) mRNA following parachlorophenylalanine (PCPA) treatment
1994, Molecular Brain Research