Elsevier

Brain Research

Volume 41, Issue 2, 22 June 1972, Pages 503-506
Brain Research

DOPA decar☐ylase in the developing rat brain

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References (16)

  • ChristensonJ.G. et al.

    Preparation and properties of a homogeneous aromaticl-amino acid decar☐ylase from hog kidney

    Arch. Biochem. Biophys.

    (1970)
  • LovenbergW. et al.

    Aromaticl-amino acid decar☐ylase

    J. biol. Chem.

    (1962)
  • BennettD.S. et al.

    Schedule of appearance of 5-hydroxytryptamine (serotonin) and associated enzymes in the developing rat brain

    J. Neurochem.

    (1965)
  • CoyleJ.T. et al.

    Development of the uptake and storage ofl-[3H]-norepinephrine in the rat brain

    J. Neurochem.

    (1971)
  • CoyleJ.T. et al.

    Dopamine-β-hydroxylase in the rat brain: developmental characteristics

    J. Neurochem.

    (1972)
  • CoyleJ.T. et al.

    Tyrosine hydroxylase in rat brain: developmental characteristics

    J. Neurochem.

    (1972)
  • GlowinskiJ. et al.

    Regional studies of catecholamines in rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]DOPA in various regions of the brain

    J. Neurochem.

    (1966)
  • HoltzP.

    Role ofl-dopa decar☐ylase in the biosynthesis of catecholamines in nervous tissue and the adrenal medulla

    Pharmacol. Rev.

    (1959)
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