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Imbalance in cerebral protein homeostasis: Effects on memory consolidation
2020, Behavioural Brain ResearchCitation Excerpt :The retention session was carried out 0.5 h after training with 0.8 mA. We expected to find normal latencies based on previous work from our laboratory showing that the same dose of CXM on learning of IA, also trained with 0.8 mA, did not disrupt learning when tested 30 min post-injection [14], and on earlier experimental findings showing equivalent effects at relatively short post-training intervals (less than 3 h) using systemic and intracerebral treatment with PSIs [25–31]. The Mann-Whitney U showed that there were no significant differences in training and escape latencies (data not shown); by the same token, there were no significant differences in retention latencies between the CXM and VEH groups at any of the time intervals studied (Fig. 4).
Anisomycin infusion in amygdala impairs consolidation of odor aversion memory
2008, Brain ResearchCitation Excerpt :The fact that Ani infusion in the pre-CS group overlaps the time of administration of both the CS and the US suggests that the formation of CS or CS–US representation has been disrupted. However, in other aversive learning, Ani infusion in BLA immediately after CS–US pairing impaired memory in fear conditioning (Schafe and LeDoux, 2000; Maren et al., 2003; Huff and Rudy, 2004; Parsons et al., 2006a) and inhibitory avoidance (Berman et al., 1978; Milekic et al., 2007; Canal and Gold, 2007). The different times of infusions (post-CS versus post-CS–US) could explain the different results.
Macromolecular synthesis, distributed synaptic plasticity, and fear conditioning
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2003, Pharmacology Biochemistry and BehaviorCycloheximide inhibits context memory and long-term habituation in the crab Chasmagnathus
1995, Pharmacology, Biochemistry and Behavior
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Present address: Department of Biochemistry, Division of Chemical Neurobiology, University of North Carolina, Chapel Hill, N.C., U.S.A.