Elsevier

Brain Research

Volume 201, Issue 2, 17 November 1980, Pages 452-458
Brain Research

Spontaneous generalized spike-wave discharges in the electrocorticograms of albino rats

https://doi.org/10.1016/0006-8993(80)91052-5Get rights and content

Abstract

Generalized epileptiform discharges occur spontaneously in the electrocorticograms of some albino laboratory rats. These discharges occur during periods of quiet wakefulness, are composed of 6–10/sec spike-wave complexes, are accompanied by locomotor arrest and often by mild clonic facial movements. The occurrence of these discharges is unrelated to surgical procedures used to create chronic recording preparations. Similar discharges and behavior have been induced in controls by injections of pentylenetetrazol.

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