Columnar organization of callosal and associational projections from rat frontal cortex
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Dense inhibitory connectivity in neocortex
2011, NeuronCitation Excerpt :Altogether, these results from the optical mapping and paired recording experiments indicate a dense inhibitory connectivity from the somatostatin-expressing interneurons within local circuits (<200 μm distance from the PC). Intracortical connectivity has long been assumed to be vertically organized (“chains” or “columns” [Lorente de Nó, 1949; Mountcastle, 1982]), and this columnar organization has been observed in the frontal cortex as well (Isseroff et al., 1984). Therefore, we reanalyzed the optical mapping data, measuring the distances between the soma of the sGFP interneurons and a line through the recorded PCs, perpendicular to the pial surface (Figure 6A); this line would correspond to the axis of a hypothetical column.
EEG responses after magnetic stimulation of prefrontal cortex in healthy subjects
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Supported by MH 00298 and MH 38546.
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Present address: Department of Isotope Research, Weizmann Institute of Science, Rehovot, Israel.
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Present address: Department of Surgery, Georgetown University School of Medicine, Washington, DC U.S.A.