Elsevier

Brain Research

Volume 491, Issue 2, 10 July 1989, Pages 379-382
Brain Research

Survival of motoneurons following axotomy is enhanced by lactation or by progesterone treatment

https://doi.org/10.1016/0006-8993(89)90075-9Get rights and content

Abstract

It was shown previously that neuron loss induced by nerve transection in the hypoglossal and facial motor nuclei of female rats could be reduced by long-term testosterone treatment following axotomy. In the present study, it is reported that such neuron loss could also be attenuated by lactation-related hormones and by progesterone treatment following axotomy.

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This work was supported by Grants 666280 and 667142 from the PSC-CUNY Research Award Program of the City University of New York and U.S. Dept. of Health & Human Services PHS Grant 2-SO7-RR07132.

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The author thanks Aida Lee, Greg Rudomen, and Mary Wong for cutting paraffin blocks and Barbara Cooper for typing the manuscript.

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