Opiate withdrawal increases glutamate and aspartate efflux in the locus coeruleus: an in vivo microdialysis study
References (27)
- et al.
Clonidine reversal of increased norepinephrine metabolite levels during morphine withdrawal
Eur. J. Pharmacol.
(1979) - et al.
Effect of naloxone-precipitated morphine withdrawal on noradrenaline release in rat hippocampus in vivo
Eur. J. Pharmacol.
(1992) - et al.
Clonidine in opiate withdrawal
Lancet
(1978) - et al.
Projections of nucleus paragigantocellularis lateralis to locus coeruleus and other structures in rat
Brain Res.
(1987) - et al.
Presynaptic inhibition by clonidine of neurotransmitter amino acid release in various brain regions
Eur. J. Pharmacol.
(1992) - et al.
Elevated basal firing rates and enhanced responses to 8-Br-cAMP in locus coeruleus in brain slices from opiate-dependent rats
Eur. J. Pharmacol.
(1992) - et al.
Clonidine reverses the increased norepinephrine turnover during morphine withdrawal in rats
Brain Res.
(1980) - et al.
Destruction of the locus coeruleus decreases physical signs of opiate withdrawal
Brain Res.
(1993) - et al.
Characterization of dopamine release in the rat medial prefrontal cortex as assessed by in vivo microdialysis: comparison to the striatum
Neuroscience
(1990) - et al.
Increase in [3H]Nitrendipine binding sites in the brain in morphine-tolerant mice
Eur. J. Pharmacol.
(1984)
Withdrawal-induced activation of locus coeruleus neurons in opiate-dependent rats: attenuation by lesions of the nucleus paragigantocellularis
Brain Res.
(1989)
NMDA receptor antagonist suppress behaviors but not norepinephrine turnover or locus coeruleus unit activity induced by opiate withdrawal
Eur. J. Pharmacol.
(1991)
Glutamate antagonists prevent morphine withdrawal in mice and guinea pigs
Neurosci. Lett.
(1991)
Cited by (194)
Opioid withdrawal and memory consolidation
2020, Neuroscience and Biobehavioral ReviewsRole of orexin type-1 receptors in paragiganto-coerulear modulation of opioid withdrawal and tolerance: A site specific focus
2017, NeuropharmacologyCitation Excerpt :Consistently, in a recent study by Kaeidi et al. (2015), it was observed that the net naloxone–induced increase in firing rate and resting membrane potential of LC neurons in slices containing both LPGi and LC neurons are significantly higher than slices lacking intact LPGi afferents. Third, glutamate and aspartate efflux has been shown to increase during opiate withdrawal within the LC (Aghajanian et al., 1994; Zhang et al., 1994). Several lines of evidence support the involvement of the LPGi in mediating opiate dependence and tolerance (Ahmadi-Soleimani et al., 2014; Ghaemi-Jandabi et al., 2014; Haghparast et al., 1998; Johnson et al., 2002; Saiepour et al., 2001; Sinchaisuk et al., 2002; Zhu and Zhou, 2010).
Sex-dependent mental illnesses and mitochondria
2017, Schizophrenia ResearchIntracoerulear microinjection of orexin-A induces morphine withdrawal-like signs in rats
2017, Brain Research Bulletin
Copyright © 1994 Published by Elsevier B.V.