Sensitization and conditioning of feeding following multiple morphine microinjections into the nucleus accumbens
References (33)
- et al.
Evidence for opiate-dopamine cross-sensitization in nucleus accumbens: studies of conditioned reward
Brain Res. Bull.
(1992) - et al.
Amphetamine- and morphine-induced feeding: evidence for involvement of reward mechanisms
Neurosci. Biobehav. Rev.
(1990) - et al.
The use of opiate antagonists in treating bulimia: a study of low-dose versus high-dose naltrexone
Psychiat. Res.
(1988) - et al.
The effect of morphine applied locally to mesencephalic dopamine cell bodies on spontaneous activity in the rat
Neurosci. Lett.
(1979) - et al.
Stimulation of food intake following opioid microinjection into the nucleus accumbens septi in rats
Peptides
(1986) - et al.
Naloxone but not CCK-8 may attenuate binge-eating behavior in patients with the bulimia syndrome
Biol. Psychiatry
(1986) - et al.
From motivation to action: functional interface between the limbic system and the motor system
Prog. Neurobiol.
(1980) - et al.
An investigation of the role of kappa opiate receptor agonists in the initiation of feeding
Life Sci.
(1982) - et al.
Increased food intake after opioid microinjections into nucleus accumbens and ventral tegmental area of rat
Brain Res.
(1986) Endogenous opioid peptides and regulation of drinking and feeding
Am. J. Clin. Nutr.
(1985)
Limbic-striatal interactions in reward-related processes
Neurosci. Biobehav. Rev.
Opioid and non-opioid components of insulin-induced feeding
Pharmacol. Biochem. Behav.
A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function
Brain Res.
Sensitization occurs to the locomotor effects of morphine and the specific μ opioid receptor agonist, DAGO, administered repeatedly to the ventral tegmental area but not to the nucleus accumbens
Brain Res.
Conditioning processes and cue exposure in the modification of excessive eating
Addictive Behav.
On the significance of subterritories in the ‘accumbens’ part of the rat ventral striatum
Neuroscience
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2022, Pharmacology Biochemistry and BehaviorCitation Excerpt :Thus, a difference in sucrose consumption in preshift sessions is not a viable explanation for the present results. Second, there is evidence suggesting that repeated stimulation of opiate receptors may enhance associative mechanisms, such that previously neutral environmental stimuli acquire the ability to elicit feeding (Bakshi and Kelley, 1994; Kelley et al., 2000). According to this view, rats exposed to RD in a context previously associated with morphine injections (Paired/Diff) could have increased sucrose consumption on session 11 based on this association.
‘Liking’ and ‘wanting’ in eating and food reward: Brain mechanisms and clinical implications
2020, Physiology and BehaviorThe influence of opioid dependence on salt consumption and related psychological parameters in mice and humans
2019, Drug and Alcohol DependenceCitation Excerpt :Cross-sensitization involving natural rewards such as sweet tastants has also been observed. For example, behavioural cross-sensitization can occur between sucrose and psychostimulants (Avena et al., 2008; Gosnell, 2005) and between opioids and food intake (Bakshi and Kelley, 1994), while a prior history of salt depletion can cross-sensitize to sugar intake (Santos et al., 2016). Further highlighting the possibility of food-drug cross-sensitization in salt consumption neuronal circuits, previous bouts of salt depletion in rats increases the locomotor effects of several drugs including morphine (Acerbo and Johnson, 2011; Clark and Bernstein, 2004; Na et al., 2009).
Endogenous opioid modulation of food intake and body weight: Implications for opioid influences upon motivation and addiction
2019, PeptidesCitation Excerpt :Correspondingly, food intake was also stimulated following repeated administration of opioid peptides, including BEND, DYN, and Enk (Table 1). Indeed, the stimulatory effects of opiates and opioids upon food intake typically sensitize rather than adapt following repeated administration [25,200,216,451]. Morphine-induced feeding has been alternatively attributed to selective increases in fat intake [297] or increased intake of those particular macronutrients consistent with the animal's baseline diet preferences [155].
Sex differences in hedonic and homeostatic aspects of palatable food motivation
2019, Behavioural Brain Research
This work was supported in part by Grant DA04788 from the National Institute on Drug Abuse.
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Present address: Dept. Neurosciences, University of California at San Diego, La Jolla, CA 92037, USA.