Unit activity in experimental epileptic foci during focal cortical hypothermia
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Rapid focal cooling attenuates cortical seizures in a primate epilepsy model
2017, Experimental NeurologyCitation Excerpt :The mechanism by which cooling controls seizures is still unclear. Some proposed mechanisms involving effects on ion transport across the cell membrane, such as alterations in passive Na2 + exchange (Moseley et al., 1972; Reynolds et al., 1975), increase of resting input resistance (Volgushev et al., 2000), or inhibition of Na+-K+-ATP enzyme were discussed (Aihara et al., 2001). Reversible reduction of neurotransmitter release and diffusion during cooling has also been reported (Boucher et al., 2010; Yang et al., 2005).
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1975, Experimental Neurology
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Supported by NIH Grant NS 04053.
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