Elsevier

Neuropsychologia

Volume 33, Issue 4, April 1995, Pages 509-523
Neuropsychologia

Focal retrograde amnesia following closed head injury: A case study and theoretical account

https://doi.org/10.1016/0028-3932(94)00136-DGet rights and content

Abstract

In this paper we present data from a closed head injury patient who presents a striking example of what Kapur (Cortex 29, 217–234, 1993) has termed “focal retrograde amnesia”. The patient, D.H., is unable to recollect any autobiographical incidents from the pre-morbid period, although he is able to provide personal and public information from this period. The data are discussed in relation to other reported instances of focal retrograde amnesia and a preliminary theoretical account is offered.

References (33)

  • J.A. Robinson

    Sampling autobiographical memory

    Cognit. Psychol.

    (1976)
  • M. Rousseaux et al.

    Amnesic retrograde post-traumatique

    Cortex

    (1984)
  • T. Shallice et al.

    The involvement of the frontal lobes in cognitive estimation

    Cortex

    (1978)
  • A. Stracciari et al.

    Post-traumatic retrograde amnesia with selective impairment of autobiographical memory

    Cortex

    (1994)
  • J. Evans et al.

    Neuropsychological and SPECT scan findings during and after transient global amnesia: Evidence for the differential impairment of remote episodic memory

    J. Neurol. Neurosurg. Psychiat.

    (1993)
  • E. Goldberg et al.

    Retrograde amnesia: Possible role of mesencephalic reticular activation in long-term memory

    Science

    (1981)
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