ArticleSensory irritation and coolness produced by menthol: Evidence for selective desensitization of irritation
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2019, Journal of Science and Medicine in SportCitation Excerpt :There is little information on the dose-response effect of menthol applied to the skin, with studies here using ∼4–8%. Perceptually, other studies have found that low concentrations of menthol (<2%) elicit cool sensations,51 moderate concentrations (2–5%) cause irritation and local anaesthesia,1 with higher concentrations (>10%) initiating burning sensations.52 Whilst further work is needed to understand this method and concentration, it should be noted that the practical application of creams and gels during exercise largely restrict its use to pre-exercise.
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