Research reportDoes the red nucleus provide the tonic support against which fractionated movements occur? A study on forepaw movements used in skilled reaching by the rat
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Cited by (56)
Cerebellospinal Neurons Regulate Motor Performance and Motor Learning
2020, Cell ReportsHeterogeneous expression of extracellular matrix molecules in the red nucleus of the rat
2016, NeuroscienceCitation Excerpt :This expression pattern might be related to the projection of the magnocellular division: it is the only output of the red nucleus to the spinal cord (Waldron and Gwyn, 1969; Brown, 1974). Electrophysiological recording of rubrospinal neurons suggested that they give a timing signal for the coordination of intermediate and distal forelimb muscles (Gibson et al., 1985; Houk et al., 1988; Whishaw et al., 1990, 1998; Whishaw and Gorny, 1996; Jarratt and Hyland, 1999). Since the activity of rubrospinal neurons is continuously modified by direct and indirect cerebellar signals (see for Morris et al., 2015) the less dense ECM assembly may contribute to the high level of synaptic plasticity to ensure the required precise movements during the reach-to-grasp behavior.
Evaluation of the anatomical and functional consequences of repetitive mild cervical contusion using a model of spinal concussion
2015, Experimental NeurologyCitation Excerpt :This model may have spared descending axons such as the CST within the dorsal column and rubrospinal and reticulospinal tracts within the lateral funiculi. The rubrospinal tract is involved in skilled limb movement (Liu et al., 1999; Whishaw and Gorny, 1996; Whishaw et al., 1992) as well as plays a role in ongoing overground locomotion (Muir and Whishaw, 2000). The reticulospinal tract plays an important role in the control of open-field locomotion (Schucht et al., 2002).
The differential contributions of the parvocellular and the magnocellular subdivisions of the red nucleus to skilled reaching in the rat
2015, NeuroscienceCitation Excerpt :The red nucleus sends output projections to several motor-related brainstem nuclei (Swenson and Castro, 1983a,b; Kennedy, 1987) as well as to the spinal cord via the rubrospinal tract (Waldron and Gwyn, 1969; Brown, 1974b; Murray and Gurule, 1979; Shieh et al., 1983; Antal et al., 1992; Küchler et al., 2002). Although a role in motor control has been attributed to the red nucleus (e.g. Jarratt and Hyland, 1999; Hermer-Vazquez et al., 2004), excitotoxic damage to this structure does not interfere with the occurrence of reaching or reaching success (Whishaw et al., 1990, 1992; Whishaw and Gorny, 1996; Whishaw et al., 1998). However, analysis of high-speed video recordings has revealed that lesions to the red nucleus abolish several components of the reaching action.
Task-dependent compensation after pyramidal tract and dorsolateral spinal lesions in rats
2009, Experimental Neurology