Short communicationPharmacological characterization of a cloned rat glutamate transporter (GluT-1)☆
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2011, Brain, Behavior, and ImmunityCitation Excerpt :Extracellular glutamate concentration is controlled by EAATs removing extracellular glutamate (Gegelashvili and Schousboe, 1997). There are five cloned EAAT subtypes (Tanaka, 1994), and EAAT-1 and EAAT-2 are primarily detected in astrocytes (Rothstein et al., 1994). The astrocytic transporters EAAT-1 and -2 are essential for protection against excitotoxicity as was shown in EAAT gene knockout experiments in mice (Rothstein et al., 1996).
Structure and functional expression of the cloned mouse neuronal high-affinity glutamate transporter
1997, Molecular Brain ResearchSchistosoma mansoni: L-glutamate-induced contractions in isolated muscle fibers; evidence for a glutamate transporter
1996, Experimental Parasitology
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I thank Dr. M. Ito for continuous encouragement. This work was supported by Special Researchers' Basic Science Program from the Institute of Physical and Chemical Research (RIKEN).
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Present address: Department of Degenerative Neurological Diseases, National Institute of Neuroscience, NCNP, 4-1-1 Ogawahigashi-cho, Kodaira, Tokyo 187, Japan. Fax: (81) (423) 46-1745.