Presence of avian pancreatic polypeptide-like immunoreactivity in catecholamine and methionine-enkephalin-containing neurones within the central nervous system
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Distribution of pancreatic polypeptide and peptide YY
2002, PeptidesCitation Excerpt :These findings may suggest a role for PYY in the development and maturation of sensory neurons. Neurons expressing PP-like material were early reported to occur also in the central nervous system (CNS) [23,29,44,47,59]. The isolation of NPY [76] and the subsequent findings of a large number of NPY-immunoreactive neurons in CNS [2] and a high content of NPY in brain [16] lead to the view that NPY represented all the PP-like material in the CNS (cf. [15]).
Roles of pancreatic polypeptide in regulation of food intake
2002, PeptidesCitation Excerpt :Furthermore, CSF PP did not increase after infusion of exogenous PP, but strenuous exercise evoked increases in both plasma and CSF PP levels [26], raising the possibility of PP release from a central source. The existence of PP-containing neurons was demonstrated in the brain [23,46]. PP mRNA has been identified in the rat brain, including the ventromedial hypothalamus, by reverse transcription-PCR [7,64].
Is there a future for neuropeptide receptor ligands in the treatment of anxiety disorders?
1999, Pharmacology and TherapeuticsNeuropeptide Y: Some viewpoints on a multifaceted peptide in the normal and diseased nervous system
1998, Brain Research Reviews
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Present address: Dept. of Psychiatry, New York University Medical Center, New York, NY, U.S.A.
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Present address: University of Kansas Medical Center, Kansas City, KS 66103, U.S.A.