MK801 induces c-fos protein in thalamic and neocortical neurons of rat brain
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Cited by (51)
Effects of dopamine and NMDA receptors on cocaine-induced Fos expression in the striatum of Fischer rats
2008, Brain ResearchCitation Excerpt :First, microdialysis studies in freely moving rats have indicated that systematic MK801 administration (0.2–0.5 mg/kg) significantly increases extracellular DA levels in the prefrontal cortex and the NAc but not in the CPu (Mathe et al., 1996; Wedzony et al., 1993; Wolf et al., 1993). In addition, previous studies indicated that moderate to high doses of MK801 (0.5–8.0 mg/kg) may induce Fos-like protein expression in various brain regions including the striatum (Dragunow and Faull, 1990; Liu et al., 1994; Storvik et al., 2006). However, in both CPu and NAc, low dose of MK801 (0.1–0.3 mg/kg) itself had no effect on c-fos mRNA induction (De Leonibus et al., 2002; Dalia and Wallace, 1995).
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