Cloning and expression of a glutamate transporter from mouse brain
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Cited by (75)
2.24 - Physiology and Pharmacology of the Cochlea
2020, The Senses: A Comprehensive Reference: Volume 1-7, Second EditionNeuronal vs glial glutamate uptake: Resolving the conundrum
2016, Neurochemistry InternationalCitation Excerpt :Antibodies were raised to the purified protein and used to localize it in the brain (Danbolt et al., 1992; Levy et al., 1993) and to screen expression libraries (Pines et al., 1992). Simultaneously, but independently of each other, three other research teams succeeded in cloning another two glutamate transporters using completely different approaches: EAAT1 (GLAST; slc1a3; Storck et al., 1992; Tanaka, 1993a) and EAAT3 (EAAC1; slc1a1; Kanai and Hediger, 1992; Kanai et al., 1993; Bjørås et al., 1996). The three human counterparts were quickly identified (Arriza et al., 1994).
Reduced excitatory amino acid transporter 1 and metabotropic glutamate receptor 5 expression in the cerebellum of fragile X mental retardation gene 1 premutation carriers with fragile X-associated tremor/ataxia syndrome
2014, Neurobiology of AgingCitation Excerpt :Disruption of this mechanism can lead to overstimulation of Glu receptors, resulting in excitotoxicity (Nakagawa and Kaneko, 2013). The family of excitatory amino acid transporters includes 5 different subtypes also known as solute carrier family 1 members, namely EAAC1/EAAT3 (Kanai and Hediger, 1992), EAAT1/SLC1a3/GLAST (Storck et al., 1992; Tanaka, 1993a, 1993b), EAAT2/SLC1a2/GLT1 (Pines et al., 1992), EAAT4 (Fairman et al., 1995), and EAAT5 (Arriza et al., 1997). Glu transporters are primarily localized in glial cells although their expression has also been detected in neurons.
Possible involvement of glutamatergic signaling machineries in pathophysiology of rheumatoid arthritis
2011, Journal of Pharmacological SciencesReverse glial glutamate uptake triggers neuronal cell death through extrasynaptic NMDA receptor activation
2009, Molecular and Cellular NeurosciencePhysiology, pharmacology and plasticity at the inner hair cell synaptic complex
2007, Hearing Research