General Pharmacology: The Vascular System
Volume 26, Issue 4, July 1995, Pages 681-696
ReviewAromatic l-amino acid decarboxylase: Biological characterization and functional role
References (156)
- et al.
Effects of l-DOPA on extracellular dopamine in striatum of normal and 6-hydroxydopamine-treated rats
Brain Res.
(1990) - et al.
Aromatic l-amino acid decarboxylase: histochemical localization in rat kidney and lack of effect of dietary potassium or sodium loading on enzyme distribution
Clin. exp. Pharmac. Physiol.
(1986) - et al.
A single gene codes for aromatic l-amino acid decarboxylase in both neuronal and non-neuronal tissues
J. biol. Chem.
(1987) - et al.
Purification of l-DOPA decarboxylase from rat liver and production of polyclonal and monoclonal antibodies against it
J. Biochem.
(1987) - et al.
Dopamine production by isolated glomeruli and tubules from rat kidneys
Can. J. Physiol. Pharmac.
(1985) - et al.
Species-specific distribution of aromatic l-amino acid decarboxylase in the rodent adrenal gland, cerebellum, and olfactory bulb
J. comp. Neurol.
(1991) - et al.
Les Catécholamines dans la maladie de Parkinson
- et al.
Variations in aromatic amino acid decarboxylase activity towards DOPA and 5-hydroxytryptophan caused by pH changes and denaturation
J. Neurochem.
(1972) - et al.
The localization of monoaminergic blood-brain barrier mechanisms
Pharmac. Rev.
(1966) - et al.
Futher studies on the inhibition of monoamine synthesis by monofluoromethyldopa
Br. J. Pharmac.
(1980)
Der L-3,4-dioxyphenylalanin (L-DOPA)—Effekt bei der Parkinson-Akinese
Wiener Klinische Wochenschrift
(1961)
The specific action of L-DOPA decarboxylase
J. Physiol. Lond.
(1939)
The amino acid decarboxylases of mammalian tissues
Adv. Enzym.
(1945)
Induction of aromatic l-amino acid decarboxylase by decarboxylase inhibitors in idiopathic parkinsonism
Ann. Neurol.
(1989)
Purification and characterization of 3,4-dihydroxyphenylalanine decarboxylase from pig kidney
Eur. J. Biochem.
(1979)
Aromatic l-amino acid decarboxylase from pig kidney
The chymotryptic phosphopyridoxal peptide of dopa decarboxylase from pig kidney
Biochem. biophys. Res. Commun.
(1977)
Biochemical properties and kinetic parameters of DOPA-5HTP decarboxylase in brain, liver, and adrenals of cat
Can. J. Biochem.
(1979)
Cerebral aryl alkyl aminergic mechanisms
Cerebral decarboxylation of meta- and para-tyrosine
Experientia
(1983)
Decarboxylation of p-tyrosine: a potential source of p-tyramine in mammalian tissues
J. Neurochem.
(1983)
Aromatic l-amino acid decarboxylase: biochemistry and functional significance
Effects of decarboxylase inhibition on the biosynthesis of brain monoamines
Life Sci.
(1962)
Activities of some enzymes which synthesize and metabolize catecholamines in the brain and peripheral organs in developing rats
Arch. Immunol. Ther. Exp. Warsz
(1975)
Changes in dopa decarboxylase mRNA but not tyrosine hydroxylase mRNA levels in rat brain following antipsychotic treatment
Psychopharmacology
(1992)
Changes in dopamine D1, D2 and D3 receptor mRNA levels in rat brain following antipsychotic treatment
Psychopharmacology
(1992)
Direct activation of calciumactivated, phospholipid-dependent protein kinase by tumor promoting phorbol esters
J. biol. Chem.
(1982)
Preparation and properties of a homogeneous aromatic L-amino acid decarboxylase from hog kidney
Arch. Biochem. Biophys.
(1970)
5-Hydroxytryptophan decarboxylase: preparation and properties
J. biol. Chem.
(1954)
Comparative and quantitative study of L-DOPA decarboxylase mRNA in rat neuronal and non-neuronal tissues
Biochem. biophys. Res. Commun.
(1990)
Localisation of human aromatic l-amino acid decarboxylase to chromosome 7p13-p11 by in situ hybridisation
Cytogenet. Cell Genet.
(1992)
Evidence for the existence of monoamine neurons in the central nervous system. I Demonstration of monoamines in cell bodies of brain stem neurons
Acta physiol. scand.
(1964)
Changes in tyrosine hydroxylase and dopa decarboxylase induced by pharmacological agents
Pharmac. Rev.
(1972)
The proportionate loss of L-3,4-dihydroxypheny-lalanine and L-5-hydroxytryptophan decarboxylating activity in rat central nervous system following intracisternal administration of 5,6-dihydroxytryptamine or 6-hydroxydopamine
J. Neurochem.
(1975)
Effects of aging on p- and m-octopamine, catecholamines and their metabolizing enzymes in the rat
J. Neurochem.
(1989)
A method for the determination of some amino acid decarboxylases
J. biol. Chem.
(1960)
Purification and characterization of rat liver 3,4-dihydrophenylalanine decarboxylase
Eur. J. Biochem.
(1987)
Where is L-DOPA decarboxylated in the striatum after 6-hydroxydopamine nigrotomy?
Brain Res.
(1978)
The biosynthesis of p-tyramine, m-tyramine, and β-phenylethylamine by rat striatal slices
J. Neurosci. Res.
(1983)
Distribution of aromatic L-amino acid decarboxylase mRNA in mouse brain by in situ hybridization histology
J. comp. Neurol.
(1993)
Ambivalence on the multiplicity of mammalian aromatic L-amino acid decarboxylase
Antipsychichotic pimozide is a potent Ca2+ channel blocker in heart
Molec. Pharmac.
(1990)
Sequence and structure of the dopa decarboxylase gene of Drosophila: evidence for novel RNA splicing variants
EMBO J.
(1986)
Catecholamine-metabolizing enzyme activity in the nigrostriatal system
Biochem. Pharmac.
(1987)
Neuroleptics of the diphenylbutylpiperidine series are potent calcium channel inhibitors
Use of d,l-alpha-monofluoromethyldopa to distinguish subcellular pools of AADC in mouse brain
Brain Res.
(1981)
Egress of endogenous DOPA from brain compromises dopamine synthesis in Parkinson's disease
J. Neurochem.
(1993)
Characterization, localization and regulation of catecholamine synthesizing enzymes
Depletion of striatal β-phenylethylamine following dopamine but not 5-HT denervation
Brain Res. Bull.
(1986)
Expression of cloned aromatic l-amino acid decarboxylase in Xenopus laevis oocytes
Neurochem. Int.
(1992)
Cited by (95)
Exploring the mechanism of compromised thermostability of aromatic L-amino acid decarboxylase from Bacillus atrophaeus through comparative molecular dynamics simulations
2023, Computational and Theoretical ChemistrySymbiont-regulated serotonin biosynthesis modulates tick feeding activity
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2020, Journal of Advanced ResearchHuman l-DOPA decarboxylase mRNA is a target of miR-145: A prediction to validation workflow
2015, GeneCitation Excerpt :l-DOPA decarboxylase (DDC) was the first decarboxylase which presence was experimentally confirmed in mammals in the late 1930s (Holtz et al., 1938). Since then, DDC has been detected in several tissues of these organisms indicating a potential implication of this enzyme in various biological processes (Zhu and Juorio, 1995). In humans, DDC has been isolated and biochemically characterized as the enzyme that is responsible for the conversion of l-3,4-dihydroxyphenylalanine (l-DOPA) to dopamine, and putatively for this of 5-hydroxytryptophan (5-HTP) to serotonin (Mappouras et al., 1990).
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