Integrin transmembrane signaling and cytoskeletal control

https://doi.org/10.1016/0955-0674(95)80110-3Get rights and content

Abstract

Integrins are remarkably multifunctional: they mediate cell adhesion and migration, orchestrate organization of the actin-based cytoskeleton, and activate signal transduction pathways. Recent studies have identified a variety of steps and hierarchies in these intracellular cytoskeletal and signaling responses, laying the groundwork for future studies on specificity and coordination with responses to growth factors.

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