Methods for ablating neurons
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Cited by (11)
Rapidly inducible, genetically targeted inactivation of neural and synaptic activity in vivo
2007, Current Opinion in NeurobiologyCitation Excerpt :A major goal in systems neuroscience is to relate the activity in specific neuronal circuits to physiological processes, behavioral responses, and disease states. This is a challenging task especially in the case of the highly complex mammalian brain and requires tools that allow rapidly inducible and reversible modulation of specific parts of neural circuits in vitro and in vivo; a need that has been widely recognized for some time [1–4]. The past decade has seen an upsurge in the development and optimization of genetically encodable tools for perturbing neuronal activity and several systems have been described [5•,6,7,8••,9•,10,11••].
In situ visualization and photoablation of individual neurons using a low cost fiber optic based system
1996, Journal of Neuroscience MethodsFacing the challenge of mammalian neural microcircuits: Taking a few breaths may help
2015, Journal of PhysiologyAblation of central nervous system progenitor cells in transgenic rats using bacterial nitroreductase system
2007, Journal of Neuroscience ResearchTargeted cell killing by reconstituted caspases
2007, Proceedings of the National Academy of Sciences of the United States of AmericaRapid Deletion of Mossy Cells Does Not Result in a Hyperexcitable Dentate Gyrus: Implications for Epileptogenesis
2004, Journal of Neuroscience
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