Elsevier

Brain Research

Volume 913, Issue 2, 21 September 2001, Pages 195-200
Brain Research

Short communication
Recurrent CA1 collateral axons in developing rat hippocampus

https://doi.org/10.1016/S0006-8993(01)02817-7Get rights and content

Abstract

Rat perinatal (E20–P0) CA1 pyramidal neurons were either synaptically active or silent. We show here that, during this developmental period, active but not silent cells form recurrent axon-collaterals that invade the radiatum and the lacunosum moleculare strata. These recurrents were never observed in adult rats. We propose that these transient recurrent axons may participate in the activity-dependent modulation of the synaptogenesis

Section snippets

Acknowledgements

We express our gratitude to Dr J. Hirsch for her advice, help and critically reading of the manuscript and to Isabel Jorquera for technical assistance.

References (26)

  • V. Crepel et al.

    Blocking GABA(A) inhibition reveals AMPA- and NMDA-receptor-mediated polysynaptic responses in the CA1 region of the rat hippocampus

    J. Neurophysiol.

    (1997)
  • S.A. Dunlop

    Transient axonal side branches in the developing mammalian optic nerve

    Cell Tissue Res.

    (1998)
  • T. Elliott et al.

    Axonal processes and neural plasticity. II: Adult somatosensory maps

    Cereb. Cortex

    (1996)
  • Cited by (0)

    View full text