Original ArticlesDiurnally Changing Effects of Locomotor Activity on Body Temperature in Laboratory Mice
Section snippets
Materials and Methods
Investigations were carried out on adult male laboratory mice of our own outbred stock (Haz:ICR), which is chronobiologically well characterized [for review, see [24]]. Animals were housed in air-conditioned rooms at an ambient temperature of 22 ± 2°C and a relative humidity of 55–65%. They were exposed to an artificial light–dark cycle (LD) of 12 h:12 h with lights on from 0700 to 1900 hours Central European Time. The illumination intensity during light time was about 150 lux. Standardized
1. Diurnal Activity and Body Temperature Rhythms
Fig. 1 shows typical diurnal changes of locomotor activity and core temperature in a male mouse with a main maximum in the dark time and a secondary maximum immediately following lights-on. The Fig. 1 illustrates the effect of activity on temperature. Nearly all changes of activity were reflected in a temperature change.
In an additional study, in which measurements were performed every minute, the relationship between locomotor activity and body temperature could be investigated in more
Discussion
The overt diurnal/circadian rhythm of body temperature consists of an endogenous and an exogenous component. The endogenous component is under the control of a circadian clock 4, 16. The exogenous component is mainly due to the activity behavior. Since motor activity produces heat, body temperature will be raised. This can be seen very clearly when comparing the diurnal patterns of locomotor activity and body temperature (Fig. 1, Fig. 2).
Others have tried to quantify the effect of activity on
References (24)
Thermal conductance in mammals and birdsIts dependence on body size and circadian phase
Comp. Biochem. Physiol.
(1981)- et al.
Brain temperature as related to gross motor activity in the unanesthetized chicken
Physiol. Behav.
(1973) Rats prefer ambient temperature out of phase with their body temperature circadian rhythm
Brain Res.
(1985)Diurnal rhythms of behavioral effects on core temperature
Physiol. Behav.
(1978)Twenty-four hour rhythms of selected ambient temperature in rat and hamster
Physiol. Behav.
(1993)Contribution of locomotor activity to the generation of the daily rhythm of body temperature in golden hamsters
Physiol. Behav.
(1994)Rhythms of body-temperature and temperature selection are out of phase in a diurnal rodent, Octodon degus
Physiol. Behav.
(1996)- et al.
The circadian rhythm of body temperature
Physiol. Behav.
(1992) - et al.
The development of circadian rhythmicity in neonates
Early Hum. Dev.
(1994) - et al.
Thermal conductance in manIts dependence on the time of day and on ambient temperature
Human circadian rhythmsA multioscillatory system
Fed. Proc.
Sleep and waking have a major effect on the 24-hr rhythm of cortical temperature in the rat
J. Biol. Rhythms
Cited by (120)
Flexibility in body temperature rhythms of free-living natal mole-rats (Cryptomys hottentotus natalensis)
2021, Journal of Thermal BiologyCitation Excerpt :Field Tb measurements can provide invaluable information regarding the thermoregulatory abilities of animals in their natural habitat and may also be used as a proxy for locomotor activity. Increased physical activity leads to an increase in Tb and changes in these two parameters are usually closely correlated (Refinetti, 1997, 1999, 1999; Refinetti and Kenagy, 2018; Tachinardi et al., 2014; Weinert and Waterhouse, 1998, 1999). In the laboratory, the daily rhythmicity in locomotor activity of Natal mole-rats (Hart et al., 2004) and several other mole-rat species (Ackermann et al., 2017; de Vries et al., 2008; Oosthuizen and Bennett, 2015; Oosthuizen et al., 2003; Schöttner et al., 2006; Vasicek et al., 2005) have been well documented.
Circadian rhythms of body temperature and locomotor activity in the antelope ground squirrel, Ammospermophilus leucurus
2018, Journal of Thermal BiologyAnalgesic effect of dimethyl trisulfide in mice is mediated by TRPA1 and sst<inf>4</inf> receptors
2017, Nitric Oxide - Biology and ChemistryCitation Excerpt :However, in the respirometry setup the mice were loosely restrained and they were unable to use an important natural thermoeffector, general locomotor activity. Since fluctuations of locomotor activity are often reflected in parallel changes of Tb in small rodents, we were also interested in thermoregulatory effects of DMTS in freely-moving mice [14,29,64]. As shown by the Tb and locomotor activity curves representing the difference between DMTS and vehicle treatment in Fig. 6, administration of DMTS (500 μmol/kg, i.p.) to TRPA1 WT and KO mice in the telemetry setup evoked a significant fall of over 4 °C in their deep Tb.