Elsevier

The Lancet

Volume 357, Issue 9270, 2 June 2001, Pages 1763-1764
The Lancet

Research Letters
Effect of sensory discrimination training on cortical reorganisation and phantom limb pain

https://doi.org/10.1016/S0140-6736(00)04890-XGet rights and content

Summary

Phantom limb pain is a frequent consequence of the amputation of a body part. Based on the finding that phantom limb pain is closely associated with plastic changes in the primary somatosensory cortex and animal data showing that behaviourally relevant training alters the cortical map, we devised a sensory discrimination training programme for patients with intractable phantom limb pain. Compared with a control group of medically treated patients, the training group had significant reductions in phantom limb pain (p=0002) and cortical reorganisation (p=0–05) that were positively associated with improved sensory discrimination ability.

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