Age-related maculopathy in a multiracial United States population: The national health and nutrition examination survey III☆
Section snippets
Population
The NHANES is a periodic national survey conducted by the National Center for Health Statistics of the Centers for Disease Control and Prevention. The NHANES is designed to provide national statistics on the health and nutritional status of the civilian noninstitutionalized population. Participation includes household interviews and standardized physical examinations.
The NHANES III survey is based on a complex, multistage area probability sample design. Children younger than 5 years of age,
Results
Weighted age- and gender-specific estimates of the prevalence of drusen, soft drusen, RPE depigmentation, increased retinal pigment, exudative macular degeneration, geographic atrophy, early ARM, and late ARM are presented in Table 4 for each of the race/ethnic subgroups. For whites, we have divided the age groups into three categories (40–59, 60–74, and ≥75 years of age). The data have been collapsed into broader age groups (40–59 and ≥60 years of age) for non-Hispanic blacks and
Comments
The NHANES III provides unique prevalence data on ARM in a nationwide, multiracial, population-based sample of persons older than 40 years of age. Standardized procedures were used for measuring risk factors and for obtaining color fundus photographs of the macula, and an objective system was used for grading these photographs for maculopathy.
In this study, after adjusting for age, the frequency of early ARM was similar in non-Hispanic whites compared with that of non-Hispanic blacks and
Acknowledgements
The authors thank Scot E. Moss, Stacy Meuer, Carol Hoyer, Moneen Meuer, Dayna Dalton, and Michael Neider for their contributions to data analysis and management. A complete list of acknowledgments can be found in the Plan and Operation of the Third National Health and Nutrition Examination Survey, 1988–1994. Programs and Collection Procedures Series 1. DHHS Publication, U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National
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2020, American Journal of OphthalmologyCitation Excerpt :The presence of DR was determined by any signs of retinopathy on fundus photograph and diagnosis of diabetes mellitus. Based on the modified Wisconsin Age-Related Maculopathy Grading Classification Scheme,51,52 the presence of soft drusen more than 500 μm in size or pigmentary abnormalities was defined as early AMD, whereas the presence of late AMD lesions, such as geographic atrophy, choroidal neovascularization, and/or subretinal fibrous scarring was defined as late AMD. The cup-to-disc ratios (CDRs) were initially measured at the University of Wisconsin.
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Supported by Centers for Disease Control and Prevention contract 200-89-7004 (Hyattsville, Maryland) (RK) and National Institutes of Health grant EYO 6594 (RK, BEKK) and, in part, by Research to Prevent Blindness (RK, Senior Scientific Investigator Award, New York, New York).