Hippocampal synaptophysin immunoreactivity is reduced during natural hypothermia in ground squirrels
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Cited by (30)
Torpor expression in juvenile and adult Djungarian hamsters (Phodopus sungorus) differs in frequency, duration and onset in response to a daily cycle in ambient temperature
2015, Journal of Thermal BiologyCitation Excerpt :The arousal from torpor is the most energy consuming phase of torpor (Thomas et al., 1990; Wojciechowski and Jefimow, 2006) and if torpor duration is too short, energy expenditure can outbalance energy savings. In addition, it should be reasonable to avoid these ineffective bouts as torpor can also impose other considerable disadvantages like sleep deficiency, oxidative stress or impaired intestinal nutrient assimilation (Carey, 1989; Daan et al., 1991; Strijkstra et al., 2003). Thus, it might be possible that the avoidance of these short torpor bouts has additionally contributed to the decreased torpor frequency, depth and duration in the cold-exposed juveniles.
Synapses, spines and kinases in mammalian learning and memory, and the impact of aging
2015, Neuroscience and Biobehavioral ReviewsCitation Excerpt :During deep hibernation, functional neuronal connectivity seems to be reduced, as the expression of synaptic markers is reduced. This reduction is, just like morphological changes, a transient alteration and restored to non-hibernating (summer) conditions within two hours (Strijkstra et al., 2003; Arendt et al., 2003). Deep torpor in ground squirrel resulted in a redistribution of hippocampal CA1 spine types: a decrease in the proportion of thin spines, and an increase in stubby and shaft spines was induced, but no change in the proportion of mushroom spines (Popov et al., 2007).
Huddling reduces evaporative water loss in torpid Natterer's bats, Myotis nattereri
2015, Comparative Biochemistry and Physiology -Part A : Molecular and Integrative PhysiologyIdentification and expression of microRNA in the brain of hibernating bats, Myotis lucifugus
2014, GeneCitation Excerpt :However, less well-known are the numerous, potentially neuroprotective aspects of hibernation such as the reversible degeneration of neuronal synapses. Torpor in hibernating animals show significant similarity to several diseases of neurodegeneration with respect to altered synaptic connectivity, the types of neurons affected, and the impairment of cognitive function (Arendt et al., 2003; Härtig et al., 2007; Millesi et al., 2001; Popov and Bocharova, 1992; Strijkstra et al., 2003; von der Ohe et al., 2006, 2007). Normal brain development and function depend on microRNA networks to fine tune the balance between the transcriptome and proteome of the cell (Masashi and Bonini, 2013).
Seasonal and sex differences in the hippocampus of a wild rodent
2013, Behavioural Brain ResearchCitation Excerpt :This is supported by studies of hibernating European (Spermophilus citellus) and long-tailed (Urocitellus undulatus) ground squirrels. Shortly following immergence into hibernation (3–11 days) in both species there is a significant decrease in dendritic branching [53–55], mossy fiber terminals [56,57] and number of synapses [58,59]. Any one, or all of, these changes could result in the observed decrease in hippocampal volume in the males without affecting either our pyramidal cell layer or granule cell layer measurements.