Ischemia-induced neuronal apoptosis
References (55)
- et al.
Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics
Br J Cancer
(1972) - et al.
Programmed cell death in Caenorhabditis elegans
Curr Opin Genet Dev
(1994) - et al.
Programmed cell death and the control of cell survival: lessons from the nervous system
Science
(1993) - et al.
The molecular mechanisms of neuronal apoptosis
Curr Opin neurobiol
(1994) - et al.
Molecular mechanisms of developmental neuronal death
Annu Rev Neurosci
(1993) Mechanisms and genes of cellular suicide
Science
(1995)Apoptosis in the pathogenesis and treatment of disease
Science
(1995)Programmed cell death: necrosis versus apoptosis
Mod Pathol
(1994)- et al.
Thymocyte apoptosis induced by p53-dependent and independent pathways
Nature
(1993) - et al.
The protooncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis
Cell
(1993)
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
J Cell Biol
(1992)
Reevaluation of the role of de novo protein synthesis in rat thymocyte apoptosis
Exp Cell Res
(1995)
Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats
Proc Natl Acad Sci USA
(1992)
Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione
J Neurosci
(1994)
Preincubation with protein synthesis inhibitors protects cortical neurons against oxygen-glucose deprivation-induced death
Neuroscience
(1996)
Cell death: the significance of apoptosis
Int Rev Cytol
(1980)
Inciting excitotoxic cytocide among central neurons
Adv Exp Med Biol
(1986)
Excitotoxic cell death
J Neurobiol
(1992)
Glutamate-induced neuronal death is not a programmed cell death in cerebellar culture
J Neurochem
(1993)
DNA strand breaks induced by sustained glutamate excitotoxicity in primary neuronal cultures
J Neurosci
(1996)
Delayed application of aurintricarboxylic acid reduces glutamate-induced cortical neuronal injury
J Neurosci Res
(1993)
Slowly-triggered excitotoxicity occurs by necrosis in cortical cultures
Neuroscience
(1996)
Potentiated necrosis of cultured cortical neurons by neurotrophins
Science
(1995)
Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-d-aspartate or nitric oxide/superoxide in cortical cell cultures
Proc Natl Acad Sci USA
(1995)
Glutamate triggers internucleosomal DNA cleavage in neuronal cells
Biochem Biophys Res Commun
(1991)
Induction of neuronal apoptosis by excitotoxins associated with long-lasting increase of 12-O-tetradecanoylphorbol 13-acetate-responsive element-binding activity
J Neurochem
(1995)
Cycloheximide and actinomycin D block the toxic effect of glutamic acid on PC12 cells
Neuroreport
(1994)
Cited by (541)
Hyperuricaemia as a prognostic factor for acute ischaemic stroke
2021, NeurologiaLow doses of methylmercury exposure during adulthood in rats display oxidative stress, neurodegeneration in the motor cortex and lead to impairment of motor skills
2019, Journal of Trace Elements in Medicine and BiologyCitation Excerpt :The main mechanism of neuronal protection played by glia consists in reducing the bioavailability of excessive glutamate in the synaptic cleft in order to avoid excitotoxicity [79]. In this way, Aschner et al. [63] exhaustively described how MeHg plays an important role in excitotoxicity, once this event propitiates the parallel intracellular calcium overload, which is related to increased Ca2+ in the mitochondrial matrix and its further dysfunction, with consecutive opening of pores in the mitochondrial membrane and release of cytochrome c and apoptotic factors, such as caspases and pro-caspases [36,80]. In this way, we believe that neuronal death is a second result of glial failure, once the neuronal microenvironment is misbalanced.
Copyright © 1996 Published by Elsevier Ltd.