Cell
Volume 127, Issue 1, 6 October 2006, Pages 49-58
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Review
Dendritic Protein Synthesis, Synaptic Plasticity, and Memory

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Considerable evidence suggests that the formation of long-term memories requires a critical period of new protein synthesis. Recently, the notion that some of these newly synthesized proteins originate through local translation in neuronal dendrites has gained some traction. Here, we review the experimental support for this idea and highlight some of the key questions outstanding in this area.

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