Cell Stem Cell
Volume 11, Issue 4, 5 October 2012, Pages 505-516
ArticleAsymmetric Segregation of the Double-Stranded RNA Binding Protein Staufen2 during Mammalian Neural Stem Cell Divisions Promotes Lineage Progression
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Graphical Abstract
Highlights
► The RNA binding protein Stau2 is asymmetrically distributed in neural progenitors ► Perturbation of Stau2 levels causes abnormal CNS progenitor behavior ► Stau2-associated transcripts include known and potentially novel fate determinants ► Asymmetric segregation of RNA networks via Stau2 contributes to cell diversification
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Present address: Department for Anatomy and Cell Biology, Ludwig Maximilian University of Munich, Schillerstrasse 42, 80336 Munich, Germany
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