Abstract
IN previous communications it has been shown that the measurement of phase change by interference microscopy can be used for determining the dry mass of living cells1, and the measurement of refractive index enables the concentration of solids and water to be calculated2. The combination of these techniques gives a method of measuring the thickness and hence the volume of living cells.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Barer, R., Nature, 169, 366 (1952).
Barer, R., and Ross, K. F. A., J. Physiol., 118, 38P (1952). Barer, R., Ross, K. F. A., and Tkaczyk, S., Nature, 171, 720 (1953).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
BARER, R. Determination of Dry Mass, Thickness, Solid and Water Concentration in Living Cells. Nature 172, 1097–1098 (1953). https://doi.org/10.1038/1721097a0
Issue Date:
DOI: https://doi.org/10.1038/1721097a0
This article is cited by
-
Artificial confocal microscopy for deep label-free imaging
Nature Photonics (2023)
-
Machine-learning-based diagnosis of thyroid fine-needle aspiration biopsy synergistically by Papanicolaou staining and refractive index distribution
Scientific Reports (2023)
-
Barrier properties of Nup98 FG phases ruled by FG motif identity and inter-FG spacer length
Nature Communications (2023)
-
Ring stage classification of Babesia microti and Plasmodium falciparum using optical diffraction 3D tomographic technique
Parasites & Vectors (2022)
-
Comprehensive single-shot biophysical cytometry using simultaneous quantitative phase imaging and Brillouin spectroscopy
Scientific Reports (2022)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.