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Dendritic release of dopamine in the substantia nigra

Nature volume 289, pages 537–543 (1981)Cite this article

Abstract

Dopamine can be released in the substantia nigra from the dendrites of nigrostriatal dopaminergic neurones, to be involved there in the self-regulation of the dopaminergic cells, to control the release of neurotransmitters from nigral afferent fibres and to influence the activity of nigral non-dopaminergic cells.

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References

  1. Bjorklund, A. & Lindvall, O. Brain Res. 83, 531–537 (1975).

    CAS  PubMed  Google Scholar 

  2. Hamori, J., Pasik, P. & Pasik, T. Adv. Neural. 14, 149–162 (1975).

    Google Scholar 

  3. Kreutzberg, G. W., Toth, L. & Kaiya, H. Adv. Neurol. 14, 269–282 (1975).

    Google Scholar 

  4. Ramon-Moliner, E. Adv. Neurol. 14, 135–148 (1975).

    Google Scholar 

  5. Shepherd, G. M. Scient. Am. 238, 92–102 (1978).

    Google Scholar 

  6. Juraska, J. M., Wilson, C. J. & Groves, P. M. J. comp. Neurol. 172, 585–600 (1977).

    CAS  PubMed  Google Scholar 

  7. Sotelo, C. J. Ultrastruct. Res. 36, 824–841 (1971).

    CAS  PubMed  Google Scholar 

  8. Parizek, J., Hassler, R. & Bak, I. J. Z. Zellforsch. mikrosk. Anat. 115, 137–148 (1971).

    PubMed  Google Scholar 

  9. Cuello, A. C. & Kelly, J. S. Br. J. Pharmac. 59, P 527–528 (1977).

    Google Scholar 

  10. Cuello, A. C. & Iversen, L. L. in Interactions between Putative Neurotransmitters in the Brain (eds Garattini, S., Pujol, J. F. & Samanin, R.) 127–149 (Raven, New York, 1978).

    Google Scholar 

  11. Sotelo, C., Javoy, F., Agid, Y. & Glowinski, J. Brain Res. 58, 269–290 (1973).

    CAS  Google Scholar 

  12. Hattori, T., Fibiger, H. C. & McGeer, P. L. J. comp. Neurol. 162, 487–504 (1975).

    CAS  PubMed  Google Scholar 

  13. Pickel, V. M., Joh, T. H., Field, P. M., Becker, C. G. & Reis, D. J. J. Histochem. Cytochem. 23, 1–12 (1975).

    CAS  PubMed  Google Scholar 

  14. Hökfelt, T., Johansson, O., Fuxe, K., Goldstein, M. & Park, D. Medbiol. Illust. 54, 427–453 (1976).

    Google Scholar 

  15. Pickel, V. M., Joh, T. H. & Reis, D. J. J. Histochem. Cytochem. 24, 792–806 (1976).

    CAS  PubMed  Google Scholar 

  16. Ljungdahl, A., Hökfelt, T., Nilsson, G. & Goldstein, M. Neuroscience 3, 945–976 (1978).

    CAS  PubMed  Google Scholar 

  17. Hattori, T., McGeer, P. L. & McGeer, E. G. Brain Res. 170, 71–83 (1979).

    CAS  PubMed  Google Scholar 

  18. Javoy, F., Hamon, M. & Glowinski, J. Eur. J. Pharmac. 10, 178–188 (1970).

    CAS  Google Scholar 

  19. Hornykiewicz, O. Wien. klin. Wschr. 75, 309–312 (1963).

    CAS  PubMed  Google Scholar 

  20. Versteeg, D. H. G. Van der Gugten,, J., De Jong, W. & Palkovitz, M. Brain Res. 113, 563–574 (1976).

    CAS  PubMed  Google Scholar 

  21. Geffen, L. B., Jessell, T. M., Cuello, A. C. & Iversen, L. L. Nature 260, 258–260 (1976).

    ADS  CAS  Google Scholar 

  22. Mercer, L., Del Fiacco, M. & Cuello, A. C. Experientia 35, 101–103 (1979).

    CAS  PubMed  Google Scholar 

  23. Wilson, C. J., Groves, P. M. & Fifkova, E. Expl Brain Res. 30, 161–174 (1977).

    CAS  Google Scholar 

  24. Korf, J., Zieleman, M. & Westerink, B. H. C. Nature 260, 257–258 (1976).

    ADS  CAS  Google Scholar 

  25. Korf, J., Zieleman, M. & Westerink, B. H. C. Brain Res. 120, 184–187 (1977).

    CAS  PubMed  Google Scholar 

  26. Westerink, B. H. C. J. Pharm. Pharmac. 31, 94–99 (1979).

    CAS  Google Scholar 

  27. Fadda, F., Argiolas, A., Stefanini, A. & Gessa, G. L. Life Sci. 21, 411–418 (1977).

    CAS  Google Scholar 

  28. Kebabian, J. W., Saavedra, J. M. & Axelrod, J. J. Neurochem. 28, 795–801 (1977).

    CAS  PubMed  Google Scholar 

  29. Hefti, F., Lienhart, R. & Lichtensteiger, W. Nature 263, 341–343 (1976).

    ADS  CAS  PubMed  Google Scholar 

  30. Pericic, D. & Walters, J. R. J. Pharm. Pharmac. 28, 527–529 (1976).

    CAS  Google Scholar 

  31. Wuerthele, S. M., Friedle, N. M. & Moore, K. E. J. Neurol. Transm. 45, 117–127 (1979).

    CAS  Google Scholar 

  32. Westerink, B. H. C. & Korf, J. Eur. J. Pharmac. 40, 131–136 (1976).

    CAS  Google Scholar 

  33. Tagerud, S. E. O. & Cuello, A. C. Neuroscience 4, 2021–2029 (1979).

    CAS  PubMed  Google Scholar 

  34. Hefti, F. & Lichtensteiger, W. J. Neurochem. 30, 1217–1230 (1978).

    CAS  Google Scholar 

  35. Hefti, F. & Lichtensteiger, W. Neurosci. Lett. 10, 65–70 (1978).

    CAS  Google Scholar 

  36. Silbergeld, E. K. & Walters, J. R. Neurosci. Lett. 12, 119–126 (1979).

    CAS  PubMed  Google Scholar 

  37. Paden, C., Wilson, C. J. & Groves, P. M. Life Sci. 19, 1499–1506 (1976).

    CAS  Google Scholar 

  38. Starr, M. S. Eur. J. Pharmac. 48, 325–328 (1978).

    CAS  Google Scholar 

  39. Reubi, J. C., Emson, P. C., Jessell, T. M. & Iversen, L. L. Naunyn Schmiedebergs Archs Pharmak. 304, 271–275 (1978).

    CAS  Google Scholar 

  40. Kerwin, E. & Pycock, C. Br. J. Pharmac. 64, 428 (1978).

    Google Scholar 

  41. Kerwin, E. & Pycock, C. Eur. J. Pharmac. 54, 93–98 (1979).

    CAS  Google Scholar 

  42. Nieoullon, A., Chéramy, A. & Glowinski, J. Nature 266, 375–377 (1977).

    ADS  CAS  Google Scholar 

  43. Wong, R. K. S., Prince, D. A. & Basbaum, A. I. Proc. natn. Acad. Sci. U.S.A. 76, 986–990 (1979).

    ADS  CAS  Google Scholar 

  44. Fukuda, J. & Kameyama, M. Brain Res. 182, 191–197 (1980).

    CAS  PubMed  Google Scholar 

  45. Llinas, R. & Hess, R. Proc. natn. Acad. Sci. U.S.A. 7, 2520–2523 (1976).

    ADS  Google Scholar 

  46. Michelot, R., Leviel, V., Giorguieff-Chesselet, M. F., Chéramy, A. & Glowinski, J. Life Sci. 24, 715–724 (1979).

    CAS  PubMed  Google Scholar 

  47. Chéramy, A., Michelot, R., Nieoullon, A., Leviel, V. & Kerdelhué, B. in Catecholamines: Basic and Clinical Frontiers Vol. 2 (eds Usdin, E., Kopin, I. J. Barchas, J.) 1098–1100 (Pergamon, New York, 1979).

    Google Scholar 

  48. Chéramy, A., Nieoullon, A. & Glowinski, J. Eur. J. Pharmac. 48, 281–295 (1979).

    Google Scholar 

  49. Nieoullon, A., Chéramy, A. & Glowinski, J. Brain Res. 145, 69–84 (1978).

    CAS  PubMed  Google Scholar 

  50. Nieoullon, A., Chéramy, A. & Glowinski, J. Brain Res. 148, 143–152 (1978).

    CAS  PubMed  Google Scholar 

  51. Leviel, V., Chéramy, A. & Glowinski, J. Nature 280, 236–239 (1979).

    ADS  CAS  Google Scholar 

  52. Greenfield, S., Chéramy, A., Leviel, V. & Glowinski, J. Nature 284, 355–357 (1980).

    ADS  CAS  Google Scholar 

  53. Nieoullon, A., Chéramy, A. & Glowinski, J. Nature 269, 340–342 (1977).

    ADS  CAS  Google Scholar 

  54. Bunney, B. S. & Aghajanian, G. K. Nature new Biol. 245, 123–125 (1973).

    CAS  PubMed  Google Scholar 

  55. Aghajanian, G. K. & Bunney, B. S. Naunyn-Schmiedebergs Archs Pharmak. 297, 1–7 (1977).

    CAS  Google Scholar 

  56. Groves, P. M., Wilson, C. J., Young, S. J. & Rebec, G. V. Science 190, 522–529 (1975).

    ADS  CAS  Google Scholar 

  57. Groves, P. M., Young, S. J. & Wilson, C. J. Neuropharmacology 15, 755–762 (1976).

    CAS  PubMed  Google Scholar 

  58. Reisine, T. D., Nagy, J. I., Fibiger, H. C. & Yamamura, H. I. Brain Res. 169, 209–214 (1979).

    CAS  PubMed  Google Scholar 

  59. Quik, M., Emson, P. C. & Joyce, E. Brain Res. 167, 355–365 (1979).

    CAS  PubMed  Google Scholar 

  60. Murrin, L. C., Gale, K. & Kuhar, M. J. Eur. J. Pharmac. 60, 229–235 (1979).

    CAS  Google Scholar 

  61. Nagy, J. I., Lee, T., Seeman, P. & Fibiger, H. C. Nature 274, 278–281 (1978).

    ADS  CAS  Google Scholar 

  62. Chéramy, A., Nieoullon, A., Michelot, R. & Glowinski, J. Neurosci. Lett. 4, 105–109 (1977).

    PubMed  Google Scholar 

  63. Nieoullon, A., Chéramy, A., Leviel, V. & Glowinski, J. Eur. J. Pharmac. 53, 289–296 (1979).

    CAS  Google Scholar 

  64. DiChiara, G., Porceddu, M. L., Spano, P. F. & Gessa, G. L. Brain Res. 130, 374–382 (1977).

    CAS  Google Scholar 

  65. Garcia-Munoz, M., Nicolau, N. M., Tulloch, I. F., Wright, A. K. & Arbuthnott, G. W. Nature 265, 363–365 (1977).

    ADS  CAS  Google Scholar 

  66. Bunney, B. S. & Aghajanian, G. K. Naunyn-Schmiedebergs Archs Pharmak 304, 255–261 (1978).

    CAS  Google Scholar 

  67. Carlsson, A. & Lindqvist, M. Acta pharmac. tox. 20, 140–144 (1963).

    CAS  Google Scholar 

  68. Chéramy, A. et al. Brain Res. 155, 404–408 (1978).

    PubMed  Google Scholar 

  69. Bunney, B. S. & Aghajanian, G. K. in The Basal Ganglia (ed. Yahr M. P.) 249–267 (Raven, New York, 1976).

    Google Scholar 

  70. Dray, A. Neuroscience 4, 1407–1439 (1979).

    CAS  Google Scholar 

  71. Reubi, J. C. & Sandri, C. Neurosci. Lett. 13, 183–188 (1979).

    CAS  Google Scholar 

  72. Prémont, J. et al. FEBS Lett. 68, 99–104 (1976).

    PubMed  Google Scholar 

  73. Spano, P. F., DiChiara, G., Tonon, G. C. & Trabucchi, M. J. Neurochem. 27, 1565–1568 (1976).

    CAS  PubMed  Google Scholar 

  74. Gale, K., Guidotti, A. & Costa, E. Science 195, 503–505 (1977).

    ADS  CAS  Google Scholar 

  75. Dray, A. & Straughan, D. W. J. Pharm. Pharmac. 28, 400–405 (1976).

    CAS  Google Scholar 

  76. Ruffieux, A. & Schultz, W. Nature 285, 240–241 (1980).

    ADS  CAS  PubMed  Google Scholar 

  77. Brown, L. L. & Wolfson, L. I. Brain Res. 140, 188–193 (1978).

    CAS  PubMed  Google Scholar 

  78. Wechsler, L. R., Savaki, H. E. & Sokoloff, I. J. Neurochem. 32, 15–22 (1979).

    CAS  PubMed  Google Scholar 

  79. Reubi, J. C., Iversen, L. L. & Jessell, T. M. Nature 268, 652–654 (1977).

    ADS  CAS  PubMed  Google Scholar 

  80. Van der Heyden, J. A. M., Venema, K. & Korf, J. J. Neurochem. 34, 119–125 (1980).

    CAS  PubMed  Google Scholar 

  81. Jessell, T. M. Proc. int. Soc. Neurochem. 6, 220 (1977).

    Google Scholar 

  82. Chéramy, A., Chesselet, M. F., Leviel, V. & Glowinski, J. (in preparation).

  83. Héry, F. et al. Brain Res. 193, 143–151 (1980).

    PubMed  Google Scholar 

  84. Jaffé, E. H. & Cuello, A. C. (in preparation).

  85. Kramer, S. G. Invest. Ophthalmol. 71, 438–52 (1971).

    Google Scholar 

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Authors and Affiliations

  1. Groupe NB—INSERM U 114, Collège de France, 11, place Marcelin Berthelot, 75231, Paris, Cedex 05, France

    A. Cheramy, V. Leviel & J. Glowinski

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  1. A. Cheramy
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Cheramy, A., Leviel, V. & Glowinski, J. Dendritic release of dopamine in the substantia nigra. Nature 289, 537–543 (1981). https://doi.org/10.1038/289537a0

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