A study reveals that a largely ignored cell type in the dentate gyrus, semilunar granule cells, are persistently depolarized after a transient input and recruit interneurons to regulate the gating of information into the hippocampus.
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References
Goldman-Rakic, P.S. Proc. Natl. Acad. Sci. USA 93, 13473–13480 (1996).
Fuster, J.M. J. Neurophysiol. 36, 61–78 (1973).
Loewenstein, Y. et al. Nat. Neurosci. 8, 202–211 (2005).
Ranganath, C. & D'Esposito, M. Neuron 31, 865–873 (2001).
Larimer, P. & Strowbirdge, B.W. Nat. Neurosci. 13, 213–222 (2010).
Shu, Y., Hasenstaub, A. & McCormick, D.A. Nature 423, 288–293 (2003).
Camperi, M. & Wang, X.-J. J. Comput. Neurosci. 5, 383–405 (1998).
Egorov, A.V., Hamam, B.N., Fransén, E., Hasselmo, M.E. & Alonso, A.A. Nature 420, 173–178 (2002).
Ramón y Cajal, S. Histology of the Nervous System (Oxford University Press, Oxford, 1995).
Williams, P.A., Larimer, P., Gao, Y. & Strowbridge, B.W. J. Neurosci. 27, 13756–13761 (2007).
Sloviter, R.S. Ann. Neurol. 35, 640–654 (1994).
Steffensen, S.C. & Henriksen, S.J. Brain Res. 538, 46–53 (1991).
Alle, H., Jonas, P. & Geiger, J.R. Proc. Natl. Acad. Sci. USA 98, 14708–14713 (2001).
Lysetskiy, M., Földy, C. & Soltesz, I. Hippocampus 15, 691–696 (2005).
Morgan, R.J. & Soltesz, I. Proc. Natl. Acad. Sci. USA 105, 6179–6184 (2008).
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Walker, M., Pavlov, I. & Kullmann, D. A 'sustain pedal' in the hippocampus?. Nat Neurosci 13, 146–148 (2010). https://doi.org/10.1038/nn0210-146
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DOI: https://doi.org/10.1038/nn0210-146
