In the presence of an electrical current through the bathing medium, the measurement of electrical potentials in solution with glass micropipettes is characterized by an error. This error is very troublesome when glass microelectrodes are used to sense the membrane potential during voltage clamping. The source of the error is identified and discussed. The construction of a microelectrode that minimizes the error is described in detail.

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Dr. A. R. Freeman of the Dept. of Physiology, Rutgers Medical School, suggested this.
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© 1970 The American Institute of Physics.
1970
The American Institute of Physics
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