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The biophysics of neuronal growth

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Published 17 August 2010 2010 IOP Publishing Ltd
, , Citation Kristian Franze and Jochen Guck 2010 Rep. Prog. Phys. 73 094601 DOI 10.1088/0034-4885/73/9/094601

0034-4885/73/9/094601

Abstract

For a long time, neuroscience has focused on biochemical, molecular biological and electrophysiological aspects of neuronal physiology and pathology. However, there is a growing body of evidence indicating the importance of physical stimuli for neuronal growth and development. In this review we briefly summarize the historical background of neurobiophysics and give an overview over the current understanding of neuronal growth from a physics perspective. We show how biophysics has so far contributed to a better understanding of neuronal growth and discuss current inconsistencies. Finally, we speculate how biophysics may contribute to the successful treatment of lesions to the central nervous system, which have been considered incurable until very recently.

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