Molecular mechanisms of synaptic plasticity and memory

Y Elgersma; A J Silva

doi:10.1016/s0959-4388(99)80029-4

Molecular mechanisms of synaptic plasticity and memory

Curr Opin Neurobiol. 1999 Apr;9(2):209-13. doi: 10.1016/s0959-4388(99)80029-4.

Authors

Y Elgersma¹, A J Silva

Affiliation

¹ Department of Neurobiology, University of California-Los Angeles, Box 951761, 695 Young Drive South, Los Angeles, California 90095-1761, USA.elgersma@ucla.edu

PMID: 10322188
DOI: 10.1016/s0959-4388(99)80029-4

Abstract

To unravel the molecular and cellular bases of learning and memory is one of the most ambitious goals of modern science. The progress of recent years has not only brought us closer to understanding the molecular mechanisms underlying stable, long-lasting changes in synaptic strength, but it has also provided further evidence that these mechanisms are required for memory formation.

Publication types

Review

MeSH terms

Amygdala / physiology
Animals
Aplysia / physiology
Avoidance Learning / physiology
Ion Channel Gating
Learning / physiology*
Long-Term Potentiation
Memory / physiology*
Neuronal Plasticity / physiology*