Amyloid production and deposition in mutant amyloid precursor protein and presenilin-1 yeast artificial chromosome transgenic mice

Nat Neurosci. 1999 Aug;2(8):695-7. doi: 10.1038/11154.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Alzheimer Disease / genetics*
  • Amyloid beta-Protein Precursor / genetics*
  • Amyloid beta-Protein Precursor / metabolism
  • Animals
  • Chromosomes, Artificial, Yeast*
  • Humans
  • Membrane Proteins / genetics*
  • Mice
  • Mice, Transgenic
  • Mutation
  • Presenilin-1
  • Reverse Transcriptase Polymerase Chain Reaction

Substances

  • Amyloid beta-Protein Precursor
  • Membrane Proteins
  • PSEN1 protein, human
  • Presenilin-1